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Preface XV

List of Contributors XVII

List of Abbreviations XXI

1. Asymmetric Organocatalysis: A New Stream in Organic Synthesis 1

2. Enamine Catalysis 19

2.1 Aldol and mannich-Type Reaction 19

2.2 a-Heteroatom Functionalization 56

2.3 Direct Conjugate Additions via Enamine Activation 77

3. Iminium Catalysis 95

4. Ammonium Ions as Chiral Templates 121

5. Orgnocatalytic Enantioselective Morita-Baylis-Hillman(MBH) Reactions 151

6. Asymmetric Proton Catalysis

7. Chiral Lewis Bases as Catalysts 255

8. Asymmetric Qcyl Transfer Reactions 287

9. Nucleophilic N-Heterocyclic Carbenes in Asymmetric Organocatalysis 331

10. Ylide-Based Reactions 357

11. Organocatalytic Enantiselective Reduction of Olefins, Keones, and Imines 391

12. Oxidation Reactions 403

13. Shape-and Site-Selective Asymmetric Reactions 425

14. Appendix I : Reaction Procedures 451

15. Appendix II : Catalysts 513

Subject Index 531

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In this reference leaders at the forefront of research provide an insight into one of the hottest topics in organic synthesis, focusing on the most important enantioselective reactions.
Clearly structured, each entry begins with a concise introduction, including a mechanistic discussion of the reaction, followed by preparative guidelines for newcomers, such as carefully selected working procedures with critical notes for bench chemists, rules of thumb and tips and tricks.

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In this reference frontline leaders in the field provide an insight into one of the hottest topics in organic synthesis, focusing on the most important enantioselective reactions in the field.
Clearly structured, each entry begins with a concise introduction, including a mechanistic discussion of the reaction. Experimental procedures are brought together in a concluding chapter: preparative guidelines for newcomers, carefully selected working procedures with critical notes for bench chemists, rules of thumb and tips and tricks.

Peter I. Dalko studied chemistry at the Budapest Technical University (Hungary) and obtained his doctorate with Dr. S. D. Gi¿½ro in Gif-sur-Yvette (France). After undertaking postdoctoral research with Sir Derek H. Barton at Texas A&M University (USA) and Prof. Yoshito Kishi at Harvard University he joined Prof. Janine Cossy's research group at the ESPCI in Paris. His current main research interest is the development of novel asymmetric reactions.