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Title page 1

Contents 2

Forewords 4

Executive summary 5

Introduction 7

1. What is at stake 9

1.1. Navigating the social, green and digital transition in the polyrisk age 9

1.2. Anticipating and embracing change: designing the new scientific enterprise and leveraging technological transformation 11

1.3. Placing Europe at the forefront of global challenges: multistakeholder partnerships 14

1.4. Leaving no one behind: why FP10 should address within-Europe regional disparities and the global impacts of its R&I actions 14

2. Designing FP10 with balance and ambition 16

2.1. What is the purpose of FP10? Goals, objectives, foresight and backcasting 16

2.2. Global and European: how can FP10 thrive in the post-2024 world? 18

2.3. Excellence-driven vs mission-oriented: a false dichotomy? 21

2.4. Bridging science, education and innovation 23

3. From Horizon Europe to FP10: coherence, simplification, agility and balance 24

3.1. Beyond the pillar structure of Horizon Europe 24

3.2. The budget and governance of FP10: bigger, bolder, simpler? 28

3.3. Radical simplification - tackling red tape and boosting accessibility in FP10 29

3.4. Economic security: should FP10 fund dual-use research? 29

3.5. An FP10 with two hemispheres 31

4. Preparing for launch: a roadmap to a successful FP10 33

4.1. Preparing for launch: shaping the R&I infrastructure and providing foresight 33

4.2. Getting FP10 right: an evidence-based, foresight-based, inclusive process 34

4.3. Nesting diversity, equity and inclusion in the DNA of EU R&I 36

4.4. Communicating FP10 and the value of R&I for the future of the EU 37

4.5. Synopsis of problems and proposed solutions 38

4.6. Open questions and avenues for future research 39

Tables 3

Table 1. Two proposed hemispheres of FP10 32

Table 2. A vision for FP10: identified problems with proposed solutions 38

Figures 3

Figure 1. A comprehensive framework for an agile, effective, balanced and coherent approach to R&I in Europe 6

Figure 2. Intermediate and ultimate goals of FP10 16

Figure 3. Foresight, backcasting and FP10 implementation: a simplified scheme 17

Figure 4. The pillar structure of Horizon Europe 24

Figure 5. A new structure for FP10 27

Figure 6. A comprehensive framework for an agile, effective, balanced and coherent approach to R&I in Europe 32

Boxes 3

Box 1. The EU Cities Mission: an example of a systemic approach to challenge-driven R&I 11

Box 2. Unleashing Europe's excellence in science through a new governance of basic research 18

Box 3. FP10 under a single competitiveness fund: some hopes, many concerns 28

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