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한국학술지인용색인(NRF)
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Background: This study was conducted to investigate the optimal time interval for tracheal intubation and the effect of adjuvant drugs such as remifentanil and lidocaine during induction and tracheal intubation using sevoflurane inhalation without muscle relaxant.
Methods: This study enrolled patients with the age of 20?60 years old and ASA 1 or 2. Patients were randomly assigned into one of 4 groups (S, SR, SRL, SL), in which they were given remifentanil (R) i.v. at a rate of 0.25μg/kg/min, or lidocaine (L) i.v. bolus of 1.5 mg/kg during sevoflurane inhalation (S). Anesthesia was performed as inhalation induction 2 minutes after pre-filling with sevoflurane 8 vol%. The time interval between induction and tracheal intubation was determined using up-and-down method. When satisfied all of the categories of response to tracheal intubation, the case was assigned to ‘success', otherwise ‘fail'. In each groups, effective time for successful intubation in 50% (ET50) and 95% (ET95) were calculated by probit analysis.
Results: ET50 was 3.90 minutes (95% confidence interval 3.32?4.38) in group S, 3.18 minutes (2.92?3.48) in group SL, 2.83 minutes (2.47?3.07) in group SR, and 2.68 minutes (2.37?2.95) in group SRL. In group S, SL, SR, and SRL, ET95 was 4.52 minutes (4.17?7.95), 3.63 minutes (3.37?4.97), 3.30 minutes (3.06?4.64), and 3.12 minutes (2.89?4.42), respectively.
Conclusions: The optimal time to intubate successfully using sevoflurane without muscle relaxant in 95% patients was 4.5 minutes. The optimal time is reduced to 3.1 minutes by coadministration of remifentanil and lidocaine.권호기사
참고문헌 (19건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | The Korean Society of Anesthesiologist: Anesthesiology and Pain Medicine. Seoul, Yumoonkak Publishing Inc. 2003, pp 151-2. | 미소장 |
| 2 | Tracheal Intubation of Healthy Pediatric Patients Without Muscle Relaxant  |
미소장 |
| 3 | Sevoflurane--a long-awaited volatile anaesthetic. |
미소장 |
| 4 | Cardiovascular effects of sevoflurane compared with those of isoflurane in volunteers. |
미소장 |
| 5 | The Comparative Effects of Sevoflurane Versus Propofol in the Induction and Maintenance of Anesthesia in Adult Patients |
미소장 |
| 6 | The Effects of the Lidocaine or Fentanyl Pretreatment on Inhalational Induction with Sevoflurane |
미소장 |
| 7 | A double‐blind comparison of codeine and morphine for postoperative analgesia following intracranial surgery |
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| 8 | Determination of sevoflurane alveolar concentration for tracheal intubation with remifentanil, and no muscle relaxant |
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| 9 | Kwak HJ, Park SY, Min SK, Kim MS, Kim JY: Inhalation induction of anesthesia with 8% sevoflurane in pediatric ambulatory surgery: Conditions for nasotracheal intubation and the effects of Dexamethasone on postoperative nausea and vomiting. Korean J Anesthesiol 2005; 48: 520-5. | 미소장 |
| 10 | Lidocaine Does Not Prevent Bispectral Index Increases in Response to Endotracheal Intubation |
미소장 |
| 11 | Good Clinical Research Practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents |
미소장 |
| 12 | Yurino M, Kimura H: Induction of anesthesia with sevoflurane, nitrous oxide, and oxygen: a comparison of spontaneous ventilation and vital capacity rapid inhalation induction (VCRII) techniques. Anesth Analg 1993; 76: 598-601. | 미소장 |
| 13 | Induction of anesthesia and tracheal intubation with sevoflurane in adults. |
미소장 |
| 14 | EFFECTS OF I.V. LIGNOCAINE ON AIRWAY REFLEXES ELICITED BY IRRITATION OF THE TRACHEAL MUCOSA IN HUMANS ANAESTHETIZED WITH ENFLURANE |
미소장 |
| 15 | Determination of end-tidal sevoflurane concentration for tracheal intubation and minimum alveolar anesthetic concentration in adults. |
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| 16 | Stoelting RK, Miller RD: Basics of Anesthesia. 4th ed. Philadelphia, Churchill Livingstone. 2000, pp 76-7. | 미소장 |
| 17 | Remifentanil Versus Alfentanil |
미소장 |
| 18 | Joo HS, Perks WJ, Belo SE: Sevoflurane with remifentanil allows rapid tracheal intubation without neuromuscular blocking agents: Can J Anaesth 2001; 48: 646-50. | 미소장 |
| 19 | Choi SJ, Gwak MS, Yang MK: Intubation conditions and responses to intubation after sevoflurane-N2O-O2 vital capacity rapid intubation induction without muscle relaxant: comparison with propofol-N2O-O2-vecuronium. Korean J Anesthesiol 2003; 44: 431-9. | 미소장 |
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