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The impact of the aortic pulse wave velocity on the cardiovascular outcomes of hemodialysis patients / Seok Joon Shin ; Yong Kyun Kim ; Sungjin Chung ; Hyun Wha Chung ; Sang Hyun Ihm ; Cheol Whee Park ; Young Ok Kim ; Ho Cheol Song ; Yong Soo Kim ; Eui-Jin Choi 1

[요약] 1

Introduction 1

Materials and methods 2

Patients 2

Biochemical assays 2

Measurement of the pulse wave velocity 2

Ambulatory blood pressure monitoring and echocardiography 2

Statistical analysis 2

Results 3

Baseline characteristics of the hemodialysis patients 3

Analysis of the aortic pulse wave velocity according to the patient groups 3

Association between AoPWV and clinical parameters 4

Cardiovascular outcomes 4

Discussion 5

REFERENCES 7

초록보기

The aims of our study were to identify the risk factors for an increased aortic pulse

wave velocity (AoPWV) and to assess the impact of the AoPWV on the cerebro-cardiovascular

(CV) outcomes of hemodialysis (HD) patients. Seventy two HD patients

were included, and the AoPWV, the echocardiography and the biochemical parameters

were measured. After dividing the patients into tertiles according to the AoPWV

values, we defined the low, the middle and the high AoPWV groups. The patients in

the high AoPWV group showed a significantly higher age and high-sensitivity C-reactive

protein level, a greater prevalence of diabetes and statin use, left ventricular

hypertrophy, average pulse pressure (PP), AoPWV and left ventricular mass index

and a lower serum albumin level than those in the low AoPWV group (p<0.05). On

multivariate regression analysis of the AoPWV, age and the average PP were

independently related to the AoPWV (p<0.05). On the multivariate Cox analysis

for CV outcomes, the AoPWV and the average PP remained significant independent

predictors of CV events. Our data suggest that an increased AoPWV is an

independent predictor for the CV outcomes of HD patients.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
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참고문헌 (31건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Munakata M, Sakuraba J, Tayama J, Furuta T, Yusa A, Nunokawa T, Yoshinaga K, Toyota T. Higher brachial-ankle pulse wave velocity is associated with more advanced carotid atherosclerosis in endstage renal disease. Hypertens Res 2005; 28: 9-14. 미소장
2 Accelerated atherosclerosis in prolonged maintenance hemodialysis. 네이버 미소장
3 Carotid arterial stiffness as a predictor of cardiovascular and all-cause mortality in end-stage renal disease. 네이버 미소장
4 Arterial calcification and pathology in uremic patients undergoing dialysis 네이버 미소장
5 Cardiac pathology in patients with end-stage renal disease maintained on hemodialysis. 네이버 미소장
6 Impact of aortic stiffness on survival in end-stage renal disease. 네이버 미소장
7 Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. 네이버 미소장
8 Left Ventricular Hypertrophy Is Associated with Arterial Stiffness and Vascular Calcification in Hemodialysis Patients 네이버 미소장
9 Association of Carotid Intima-Medial Thickness and Indices of Arterial Stiffness With Cardiovascular Disease Outcomes in CKD 네이버 미소장
10 Reproducibility of pulse-wave analysis and pulse-wave velocity determination in chronic kidney disease 네이버 미소장
11 Recommendations for Quantitation of the Left Ventricle by Two-Dimensional Echocardiography 네이버 미소장
12 Carotid Wall Thickness is Predictive of Incident Clinical Stroke: The Atherosclerosis Risk in Communities (ARIC) Study 네이버 미소장
13 Covic A, Mardare N, Gusbeth-Tatomir P, Prisada O, Sascau R, Goldsmith DJ. Arterial wave reflections and mortality in haemodialysis patients--only relevant in elderly, cardiovascularly compromised? Nephrol Dial Transplant 2006; 21: 2859-66. 미소장
14 The arterial system in hypertension. A prospective view. 네이버 미소장
15 Wada T, Kodaira K, Fujishiro K, Maie K, Tsukiyama E, Fukumoto T, Uchida T, Yamazaki S. Correlation of ultrasound-measured common carotid artery stiffness with pathological findings. Arterioscler Thromb 1994; 14: 479-82. 미소장
16 Cardiac and arterial interactions in end-stage renal disease. 네이버 미소장
17 Correlations between the Left Ventricular Diastolic Function and Aortic Stiffness in Healthy Aged Subjects 소장
18 Aortic and large artery compliance in end-stage renal failure. 네이버 미소장
19 Wave reflections and cardiac hypertrophy in chronic uremia. Influence of body size. 네이버 미소장
20 Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure. 네이버 미소장
21 Cross-sectional and 4-year longitudinal associations between brachial pulse pressure and common carotid intima-media thickness in a general population. The EVA study. 네이버 미소장
22 Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering. 네이버 미소장
23 Effect of atorvastatin on regional arterial stiffness in patients with type 2 diabetes mellitus. 네이버 미소장
24 Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis. 네이버 미소장
25 Wave reflection in the systemic circulation and its implications in ventricular function. 네이버 미소장
26 Therapeutic studies and arterial stiffness in hypertension: recommendations of the European Society of Hypertension 네이버 미소장
27 Normal Vascular Aging: Differential Effects on Wave Reflection and Aortic Pulse Wave Velocity: The Anglo-Cardiff Collaborative Trial (ACCT) 네이버 미소장
28 Assessment of central and peripheral arterial stiffness: studies indicating the need to use a combination of techniques. 네이버 미소장
29 Differential Impact of Blood Pressure–Lowering Drugs on Central Aortic Pressure and Clinical Outcomes: Principal Results of the Conduit Artery Function Evaluation (CAFE) Study 소장
30 Correlation between pulse wave velocity and other measures of arterial stiffness in chronic kidney disease. 네이버 미소장
31 Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humans. 네이버 미소장