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국회도서관 홈으로 정보검색 소장정보 검색

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Background: The opportunistic fungus Candida albicans is a major pathogen especially to immunocompromised patients.

Objectives: We examined the protective effect of the active and passive immunizations to evaluate the applicability for the treatment of candidosis in Candida-infected mice model.

Methods: Candida cell wall components were obtained by treatment of lyticase, proteinase K, and dithiothreitol. The proteinase was purified from the culture filtrates of C. albicans using a series of chromatographic steps consisting of DEAE-Sepharose FF, Sephacryl S-200 HR and size-exclusion

high performance liquid chromatography. The phospholipase was purified from the culture supernatant of C. albicans with DEAE column chromatography, reverse phase column chromatography, revere

phase HPLC and size-exclusion HPLC. Antibodies to cell wall protein components, proteinase and phospholipase were produced by immunization into mice of same strain.

Results: The mean survival times of active and passive immunized mice groups were longer than those of non-immunized groups.

Conclusion: These results showed that immunization with proteinase and its antibody were the most effective to prolong survival time in Candida-infected mice.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
두경부 아토피피부염 환자에서 연령과 중증도에 따른 Malassezia 균종과 Pityrosporum ovale 특이 IgE의 차이 문형식 ;손숙자 ;박 건 ;채정돈 pp.1-8

Candida albicans의 단백질분해효소, 인지질분해효소 및 세포벽 단백분획으로 면역시킨 생쥐에서의 칸디다증 방어 효과 신운섭 ;최선주 ;양영철 ;박수정 ;박주영 ;김수기 ;이경호 pp.9-15

Fluconazole 첨가 사브로덱스트로오스 한천 배지를 사용한 Candida 종의 Fluconazole 내성 검색 이미경 ;김태형 pp.16-22

햄스터에서 전염된 것으로 생각되는 Microsporum canis에 의한 백선종창 1예 김수호 ;서무규 ;김재홍 ;하경임 ;김정란 pp.23-27

한 가족에서 발생한 만성 점막피부칸디다증 최광현 ;김혜성 ;김형옥 ;박영민 pp.28-32

참고문헌 (21건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
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