본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

초록보기



In photodynamic therapy (PDT), oxygen plays important role. Because of singlet oxygen which is produced by

activated photosensitizer after laser irradiation of specific wavelength. The aim of this study is to find how oxygen

concentration affects anticancer effect in PDT. Groups were divided into PDT with oxygen applied group and only PDT

applied group. PDT with oxygen applied group supplied oxygen for 15 minute before laser irradiation. In vitro, CT-26

cell was incubated with various concentration of photofrin (50.0~0.05 μg/ml) and was irradiated with 632 nm diode

laser 6 hr after application of photofrin. The cell viability of two groups was assessed by MTT assay. In vivo, CT-26

cell line was transplanted into the subcutaneous tissue of BALB/c mouse. The anticancer effect of two groups was

measured by tumor volume change. In vitro study, the cell viability was significantly decreased at 1.56~3.13 μg/ml in

PDT with oxygen applied group. In vivo study, the PDT with oxygen applied group significantly higher reduction rate

of tumor volume 7 days after PDT compared to PDT only group. The high oxygen concentration might enhance the

anticancer effect of the photodynamic therapy.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Formation of DNA-protein crosslink at oxidized abasic site mediated by human DNA polymerase iota and mitochondrial DNA polymerase gamma Mi-Young Son ; Hyun-Ik Jun ; Sun Young Goo ; Jung-Suk Sung pp.1-8

Age at menarche and brachial-ankle pulse wave velocity in women with metabolic syndrome Yoon-Kyung Jo ; Jee Aee Im pp.9-15

Prevalence of patent foramen ovale and diagnostic efficacy of transcranial doppler sonography in cryptogenic ischemic stroke patients Dae Sik Kim ; Byung Weon Kim ; Sung Jun Cho pp.17-23

Change of somatostatin-immunoreactive cells on the stomach of ovariectomized rats Jeong Hyun Chang pp.25-29

CACNA1A gene polymorphism is associated with hypertension in Korean population Hye Kyung Kim ; Kang Hyun Leem ; Sena Lee ; Mee Sook Hong ; Kyung Hee Jung ; Su Kang Kim ; Sung Wook Kang ; Joo-Ho Chung pp.31-35

Production of recombinant protein, human stem cell factor, using insect cell line Sang-Mi Park ; Kisang Kwon ; Tae Won Goo ; Eun Young Yun ; Seok Woo Kang ; Sung Wan Kim ; Kweon Yu ; 권오유 pp.37-45

Evaluation of NMP22 measurement and SurePath™ liquid-based cytology for the diagnosis of bladder cancer and comparison with findings on atypical urothelial cast in voided urine sediments June Taek Lee ; Ji-Sook Lee ; In Sik Kim pp.47-53

Effects of pentoses on 2-deoxy-D-Glucose transport of the endogenous sugar transport systems in spodoptera frugiperda clone 9 cells 이종기 pp.55-60

A77 1726 inhibit NO-induced apoptosis via PI-3K/AKT signaling pathway in rabbit articular chondrocyte In-Kyou Choi ; 김송자 pp.61-66

Paclitaxel suppress dedifferentiation via mitogen-activated protein kinase pathway in rabbit articular chondrocyte Jeong Hee Im ; 김송자 pp.67-72

Antibacterial activity of ciprofloxacin-incorporated central venous catheters and its mechanism against planktonic bacterial cells Sung Min Jeon ; 김말남 pp.73-80

Histological change and collagen formation on laser wounded rat using 808 nm diode laser and CO₂laser Phil-Sang Chung ; Jang-In Shin ; So-Young Chang ; 안진철 pp.81-86

Enhancement of Anticancer effect through photodynamic therapy with high oxygen concentration Yun-Ho Kim ; Phil-Sang Chung ; Sang Joon Lee ; Jang-In Shin ; Heejun Hwang ; 안진철 pp.87-91

Chemotactic effect of the house dust mite allergen, Dermatophagoides pteronyssinus on human monocytic THP-1 cells Eun Ju Yang ; Ji-Sook Lee ; Chi-Young Yun ; In Sik Kim pp.93-96

Analysis of genes regulated by HSP90 inhibitor geldanamycin in neurons Young Mo Yang ; Seung-Whan Kim ; 권오유 pp.97-99

Association of hepatocyte nuclear factor-4α (HNF-4α) polymorphisms (rs1884614) with type 2 diabetes in Korean population Su-Won Kim ; 유 민 pp.101-103

참고문헌 (19건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Ball DJ, Luo Y, Kessel D, Griffiths J, Brown SB, Vernon DI. The induction of apoptosis by a positively charged methylene blue derivative. J Photochem Photobiol B 1998. 42: 159-163. 미소장
2 ROS Formation and the Mechanism of Photodynamic Therapy Using 9-Hydroxypheophorbide-a on AMC-HN3 Human Head and Neck Carcinoma Cell Line 소장
3 An update on photodynamic therapy applications. 네이버 미소장
4 Foote CS. Type I and Type II mechanisms of photodynamic action. In: Heitz JR, Downum KR, editors. Light-Activates Pesticides. Washington D: Am Chem Soci. 1987. 22-38. 미소장
5 The Role of Oxygen in Cutaneous Photodynamic Therapy 네이버 미소장
6 Hampton JA, Selman SH. Mechanism of cell killing in photodynamic therapy using a novel in vivo drug/in vitro light culture system. Photochem. Photobial. 1992. 56: 235-243. 미소장
7 Hematoporphyrin Derivative: A Possible Aid in the Diagnosis and Therapy of Carcinoma of the Bladder 네이버 미소장
8 The Role of Subcellular Localization in Initiation of Apoptosis by Photodynamic Therapy 네이버 미소장
9 A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy. 네이버 미소장
10 Subcellular distribution and photocytotoxicity of aluminium phthalocyanines and haematoporphyrin derivative in cultured human meningioma cells. 네이버 미소장
11 The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen. 네이버 미소장
12 Ochsner M. New trends in photobiology. Photophysical and photobiological processes in the photodynamic therapy of tumors. Photochem Photobiol. 1997. 39: 1-18. 미소장
13 Antitumor effect of 5-aminolevulinic acid-mediated photodynamic therapy can be enhanced by the use of a low dose of photofrin in human tumor xenografts. 네이버 미소장
14 Ripson RL, Blades EJ, Olsen AM. The use of hematoporphyrin in tumor destruction. J Natl Cancer Inst. 1961. 26: 1-11. 미소장
15 In vivo tumor oxygen tension measurements for the evaluation of the efficiency of photodynamic therapy. 네이버 미소장
16 Current status of photodynamic therapy in oncology. 네이버 미소장
17 Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements. 네이버 미소장
18 Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. 네이버 미소장
19 Differential cell death response to photodynamic therapy is dependent on dose and cell type. 네이버 미소장

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기