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Biotransformation is often used to improve chemical activity.

We evaluated the antimicrobial activity of rhapontigenin,

converted from rhapontin after treatment with Pectinex.

Rhapontigenin showed 4?16 times higher antimicrobial

activity than rhapontin. The activity was higher against

Gram-positive strains than Gram-negative strains. Minimum

inhibitory concentrations (MICs) of rhapontigenin, retinol,

and five antibiotics were determined by the microbroth

dilution method for antibiotic-sensitive and -resistant

Propionibacterium acnes. We also investigated the in vitro

antibacterial activity of rhapontigenin in combination

with antibiotic against antibiotic-resistant P. acnes. The

antibiotic combination effect against resistant P. acnes

was studied by the checkerboard method. The combination

formulations (rhapontigenin and clindamycin, retinol and

clindamycin) showed synergistic effects on the inhibition of

the growth of clindamycin-resistant P. acnes. It is predictable

that the combination of antibiotics with rhapontigenin

is helpful to treat acne caused by antibiotic-resistant

P. acnes. The antibacterial activity of rhapontigenin was

enhanced by biotransformation.

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권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
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Caulobacter ginsengisoli sp. nov., a novel stalked bacterium isolated from ginseng cultivating soil Liu, Qing-Mei ;Leonid N. Ten ;Wan-Taek Im ;Sung-Taik Lee ;Min-Ho Yoon pp.15-20

Monitoring the bacterial community dynamics in a petroleum refinery wastewater membrane bioreactor fed with a high phenolic load Silva, Cynthia C ;Aline F. Viero ;Ana Carolina F. Dias ;Fernando D. Andreote ;Ederson C. Jesus ;Serg pp.21-29

Unbalanced restriction impairs SOS-induced DNA repair effects Katna, Anna ;Robert Boratynski ;Beata Furmanek-Blaszk ;Natalia Zolcinska ;Marian Sektas pp.30-38

Method development for electrotransformation of Acidithiobacillus caldus Chen, Linxu ;Jianqun Lin ;Bing Li ;Jianqiang Lin ;Xiangmei Liu pp.39-44

Efficient and precise construction of markerless manipulations in the Bacillus subtilis genome Yu, Haojie ;Xin Yan ;Weiliang Shen ;Yujia Shen ;Ji Zhang ;Shunpeng Li pp.45-53

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참고문헌 (33건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Metabolites of the "smoke tree", Dalea spinosa, potentiate antibiotic activity against multidrug-resistant Staphylococcus aureus. 네이버 미소장
2 Hyphal Growth Promotion In vitro of the VA Mycorrhizal Fungus, Gigaspora margarita Becker and Hall, by the Activity of Structurally Specific Flavonoid Compounds Under CO2-Enriched Conditions 네이버 미소장
3 Chivot, M. 2005. Retinoid therapy for acne. Am. J. Clin. Dermatol. 6: 13-19. 미소장
4 Prevalence of antibiotic‐resistant propionibacteria on the skin of acne patients: 10‐year surveillance data and snapshot distribution study 네이버 미소장
5 Antimicrobial Activity of Non-Halogenated Phenolic Compounds 네이버 미소장
6 Activity and mechanism of the action of zeylasterone against Bacillus subtilis. 네이버 미소장
7 Bioprotective properties of seaweeds: in vitro evaluation of antioxidant activity and antimicrobial activity against food borne bacteria in relation to polyphenolic content. 네이버 미소장
8 Estevinho, L., A. P. Pereira, L. Moreira, L. G. Dias, and E. Pereira. 2008. Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey. Food Chem. Toxicol. 46: 3774-3779. 미소장
9 Biotechnology in Turkey: an overview. 네이버 미소장
10 Inhibitors from Rhubarb on Lipopolysaccharide-Induced Nitric Oxide Production in Macrophages: Structural Requirements of Stilbenes for the Activity 네이버 미소장
11 Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of rheum undulatum by human intestinal bacteria and their anti-allergic actions. 네이버 미소장
12 Antibacterial activity of akyl gallates against Bacillus subtilis. 네이버 미소장
13 Enzymes involved in the bioconversion of ester‐based prodrugs 네이버 미소장
14 Biotransformation of common bean (Phaseolus vulgaris L.) flavonoid glycosides by bifidobacterium species from human intestinal origin. 네이버 미소장
15 Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides. 네이버 미소장
16 Mori, A., C. Nishino, N. Enoki, and S. Tawata. 1987. Antibacterial activity and mode of action of plant flavonoids against Proteus vulgaris and Staphylococcus aureus. Phytochemistry 26: 2231- 2234. 미소장
17 National Committee for Clinical Laboratory Standards. 1997. Methods for antimicrobial susceptibility testing of anaerobic bacteria: Tentative Standard M11-A4. National Committee for Clinical Laboratory Standards, Villanova. 미소장
18 Bioavailability is improved by enzymatic modification of the citrus flavonoid hesperidin in humans: a randomized, double-blind, crossover trial. 네이버 미소장
19 European surveillance study on the antibiotic susceptibility of Propionibacterium acnes 네이버 미소장
20 A comparison of changes in the transformation of isoflavones in soymilk using varying concentrations of exogenous and probiotic‐derived endogenous β‐glucosidases 네이버 미소장
21 Antithrombotic and Antiallergic Activities of Rhaponticin from Rhei Rhizoma Are Activated by Human Intestinal Bacteria 소장
22 The antibacterial activity of topical retinoids: the case of retinaldehyde. 네이버 미소장
23 Table olives from Portugal: phenolic compounds, antioxidant potential, and antimicrobial activity. 네이버 미소장
24 Pillai, S. K., R. C. Moellering, and G. M. Eliopoulos. 2005. Antimicrobial combinations, pp. 365-440. In V. Lorian (ed.). Antibiotics in Laboratory Medicine. Lippincott Williams & Wilkins, PA, U.S.A. 미소장
25 Bioactive berry compounds-novel tools against human pathogens. 네이버 미소장
26 Enzyme-assisted processing increases antimicrobial and antioxidant activity of bilberry. 네이버 미소장
27 Racchach, M. 1984. The antimicrobial activity of phenolic antioxidants in foods: A review. J. Food Safety 6: 141-170. 미소장
28 Rauha, J. P., S. Remes, M. Heinonen, A. Hopia, M. Kahkonen, T. Kujala, K. Pihlaja, H. Vuorela, and P. Vuorela. 2000. Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds. Int. J. Food Microbiol. 56: 3-12. 미소장
29 Roupe, K. A., G. L. Helms, S. C. Halls, J. A. Yáñez, and N. M. Davies. 2005. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: Applications to metabolism, pharmacokinetics and anti-cancer studies. J. Pharm. Pharm. Sci. 8: 374-386. 미소장
30 Antimicrobial activity of tibezonium (TBZ). 네이버 미소장
31 Comparative study on the antibacterial activity of phytochemical flavanones against methicillin-resistant Staphylococcus aureus 네이버 미소장
32 Induction of proinflammatory cytokines by a soluble factor of Propionibacterium acnes: implications for chronic inflammatory acne. 네이버 미소장
33 Rhapontigenin from Rheum undulatum Protects Against Oxidative-Stress-Induced Cell Damage Through Antioxidant Activity 네이버 미소장

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