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Background : Stroke is the second leading cause of death in Korea, following cancer. Stroke consists of ischemic and hemorrhagic stroke, and ischemic stroke can be largely classified as atherothrombotic stroke or embolic stroke. Carotid intima-media thickness (IMT) is an indicator of atherosclerosis used commonly as a screening test for abnormalities of the coronary artery. 24-hour ambulatory ECG is widely used to screen for underlying diseases that causes syncope, palpitation, arrhythmia, etc.

Objectives : Since both carotid IMT and 24-hour ambulatory ECG are used to screen for cardiac problems, we endeavored to explore the correlation between carotid IMT and 24-hour ambulatory ECG of stroke patients.

Methods : The records of ischemic stroke patients who were admitted to Kyunghee Medical Center Oriental Hospital ward from March 2006 to May 2009 were reviewed. 28 patients who had both carotid Doppler US and 24-hour ambulatory ECG test undertaken during their admission were analyzed. The relationship of abnormal ambulatory results and common carotid artery(CCA) IMT were statistically analyzed using Fisher's exact test and t-test.

Results : The mean age of the abnormal ambulatory group was older than the normal group (74?.0 vs. 61?2.1, p=0.0098). Although insignificant, the abnormal ambulatory group showed much thicker CCA-IMT than normal ambulatory group (2.17?1.16 vs. 1.51?.97, p=0.1389).

Conclusion : No significant correlation was observed between abnormal ambulatory results and CCA-IMT. However, the difference in CCA-IMT between the two groups was too big to be ignored and further investigation with larger and better controlled trials are warranted.

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참고문헌 (21건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 대한민국 통계청. 사망원인통계(전국편, 2007년). 2007. 미소장
2 Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. 네이버 미소장
3 Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. 네이버 미소장
4 Carotid plaque compared with intima-media thickness as a predictor of coronary and cerebrovascular disease 네이버 미소장
5 Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. 네이버 미소장
6 Guidelines for management of ischaemic stroke and transient ischaemic attack 2008. 네이버 미소장
7 The Relationship between Left Ventricle Diastolic Dysfunction and Carotid Plaques in Elderly Patients with Ischemic Stroke 소장
8 Salonen R, Salonen JT. Determinants of carotid intima-media thickness: A population-based ultrasonography study in eastern finnish men J Intern Med. 1991;229(3):225-31. 미소장
9 Carotid atherosclerosis is a stronger predictor of myocardial infarction in women than in men: a 6-year follow-up study of 6226 persons: the Tromsø Study. 네이버 미소장
10 Common Carotid Intima-Media Thickness and Risk of Stroke and Myocardial Infarction 네이버 미소장
11 한국형 중풍변증 표준안-Ⅱ에 대한 보고 소장
12 Prevalence of atrial fibrillation and association of atrial fibrillation with prior and new thromboembolic stroke in older patients. 네이버 미소장
13 Relationship Between Carotid Intima-Media Thickness and Symptomatic and Asymptomatic Peripheral Arterial Disease 네이버 미소장
14 ACC/AHA Guidelines for Ambulatory Electrocardiography: Executive Summary and Recommendations 네이버 미소장
15 Antman Elliott M, Selwyn Andrew P, Braunwald Eugene, Loscalzo Joseph. Harrison's principles of internal medicine. 17th ed: McGraw Hill; 2008, p. 1514-27. 미소장
16 Cardiological diagnostic work-up in stroke patients--a comprehensive study of test results and therapeutic implications. 네이버 미소장
17 Value of Routine Holter Monitoring for the Detection of Paroxysmal Atrial Fibrillation in Patients With Cerebral Ischemic Events 네이버 미소장
18 Usefulness of Ambulatory 7-Day ECG Monitoring for the Detection of Atrial Fibrillation and Flutter After Acute Stroke and Transient Ischemic Attack 네이버 미소장
19 Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage. 네이버 미소장
20 Carotid Artery Intimal-Medial Thickness Distribution in General Populations As Evaluated by B-Mode Ultrasound 네이버 미소장
21 A Study on the Correlation of Metabolic Syndrome and Intima-media Thickness of Common Carotid Artery with Sasang Constitution 소장