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Adrenocortical carcinoma is a rare neoplasm and it has an invariably lethal prognosis. We report here on the fine needle aspiration cytologic findings of a solitary metastatic pulmonary adrenocortical carcinoma in a 24-year-old woman. The aspirate smears were very cellular and they were composed of a monomorphic population of large polyhedral cells with abundant granular or vacuolated cytoplasm, and the cells were predominantly singly scattered in a necrotic background. Multinucleated pleomorphic tumor cells were also found. Pleomorphic nuclei with thickened nuclear membranes were impinging on the cell membranes. Mitotic activity was occasionally seen. The cytologic findings of pleomorphic cells with microvacuolated cytoplasm and the presence of vague gland-like sheets, as well as the patient’ history of undergoing adrenalectomy for primary adrenocortical carcinoma helped the pathologist reach the diagnosis of metastatic adrenocortical carcinoma. Here, we focus on the cytologic differential points of metastastic pulmonary adrenocortical carcinoma and primary pulmonary carcinoma, especially large cell carcinoma.

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참고문헌 (12건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Clinical management of malignant adrenal tumors 네이버 미소장
2 Medeiros LJ, Weiss LM. (1996),Adrenal gland: tumors and tumor-like lesions. In: Weidner N, ed. The difficult diagnosis in surgical pathology. Philadelphia: WB Saunders, 377-407. 미소장
3 Pulmonary metastases of endocrine origin: the role of surgery. 네이버 미소장
4 Diagnosis and management of adrenal cortical carcinoma 네이버 미소장
5 Fine needle aspiration biopsy cytology of primary and metastatic pulmonary tumors. 네이버 미소장
6 Adrenocortical carcinoma: diagnosis by fine needle aspiration cytology. 네이버 미소장
7 Pathologic features of prognostic significance in adrenocortical carcinoma. 네이버 미소장
8 Fine-needle aspiration of adrenal cortical carcinoma: cytologic spectrum and diagnostic challenges. 네이버 미소장
9 Morphologic characteristics of benign and malignant adrenocortical tumors. 네이버 미소장
10 Fine‐needle aspiration cytology of a case of oncocytic adrenocortical carcinoma 네이버 미소장
11 Fine Needle Aspiration Cytology of Metastatic Hepatic Adrenocortical Carcinoma Mimicking Hepatocellular Carcinoma: A Case Report 네이버 미소장
12 Hiroshima K, Abe S, Ebihara Y, et al. (2005),"Cytological characteristics of pulmonary large cell neuroendocrine carcinoma.", Lung Cancer ,48, pp. 331-337. 미소장