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결과 내 검색

동의어 포함

초록보기

1. Objectives

4 herbal formulas (Yanggyeoksanhwa-tang, Yeoldahanso-tang, Cheongsimyeonja-tang and Taeeumjowi-tang) were applied to investigate the anti-inflammatory activities. In many studies, plant-derived anti-inflammatory efficacies have been investigate for their potential inhibitory effects on lipopolysaccharide (LPS)-stimulated macrophages. This study was performed to examine the anti-inflammatory activities of 4 herbal formulas on LPS-stimulated RAW 264.7 cells.

2. Methods

The productions of nitric oxide (NO), prostaglandin (PG)E2, interleukin(IL)-6 and tumor necrosis factor (TNF)-α were examined in the presence of the 4 herbal formulas in RAW 264.7 cells. The cells were incubated with LPS 1 μg/mL and 4 herbal formulas for 18 hrs. The anti-inflammatory activity of 4 herbal formulas were investigate by carrageenin-induced paw edema in rats. The paw volume was measured at 2 and 4 hrs following carrageenin- induced paw edema in rats.

3. Results

Yanggyeoksanhwa-tang and Cheongsimyeonja-tang showed inhibitory effect on PGE2 production in LPS-stimulated RAW 264.7 cells and a reduction in carrageenin-induced paw edema on rats. Yanggyeoksanhwa-tang showed inhibi- tory effect on IL-6 in LPS-stimulated RAW 264.7 cells. 4 herbal formulas not affect on NO and TNF-α inhibition in LPS-stimulated RAW 264.7 cells.

4. Conclusions

These results suggested that Yanggyeoksanhwa-tang and Cheongsimyeonja-tang have anti-inflammatory activity.

권호기사

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참고문헌 (27건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
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3 The Clinical Efficacy of Yangkyuksanwha-tang on Acute Stroke 소장
4 Jung SI, Kim JW. Clinical Study about the Diabetes Mellitus Patients Administration of Yangkyuksanwhatang.Korea J Oriental Physiology & Pathology. 2002;16(6):1308-1313. (Korean) 미소장
5 Yun BH, Park SS. Yangkyuksanhwa-tang effected to atopic dermatitis. J Sasang Constitut Med. 2004;16(2):84-98. (Korean) 미소장
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7 Kim TH, Hong SY, Han DN, Lim EC. The Effects of constant use of Yeoldahanso-tang on liver function.J Sasang Constitut Med. 2007;19(3):217-226. (Korean) 미소장
8 Lim JP, Ahn TW. The anti-oxidative and immune-regluatory effect of Chungsimyeonja-tang in aged rat. J Sasang Constitut Med. 2007;19(3):227-241.(Korean) 미소장
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13 Yun BH, Park SS. Yangkyuksanhwa-tang effected to atopic dermatitis. J Sasang Constitut Med. 2004;16(2):84-98. (Korean) 미소장
14 Won JS. Dongeuisasangshinpyeon. Seoul:Munw- oosa.1926:2. 미소장
15 Co-regulation between cyclo-oxygenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation. 네이버 미소장
16 Methanol extracts of Stewartia koreana inhibit cyclooxygenase-2(COX-2) and inducible nitric oxide synthase (iNOS) gene expression by blocking NF-κB transactivation in LPS-activated RAW 264.7 cells 소장
17 Geranylgeranylacetone Induces Cyclooxygenase-2 Expression in Cultured Rat Gastric Epithelial Cells Through NF-κB 네이버 미소장
18 Nitric oxide synthases: Roles, tolls, and controls 네이버 미소장
19 The Nitric Oxide Theory of Aging Revisited 네이버 미소장
20 Kawamata H, Ochiai H, Mantani N, Terasawa K.Enhanced expression of inducible nitric oxide synthases by Juzen-taiho-to in LPS-activated RAW264.7 cells, a murine macrophage cell line. Am J Chin Med.2000;28(2):217-226. 미소장
21 Pharmacological and Biochemical Demonstration of the Role of Cyclooxygenase 2 in Inflammation and Pain 네이버 미소장
22 Prostaglandins as mediators of COX-2 derived carcinogenesis in gastrointestinal tract 네이버 미소장
23 Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. 네이버 미소장
24 The local anti-inflammatory action of dexamethasone in the rat carrageenin oedema model is reversed by an antiserum to lipocortin 1. 네이버 미소장
25 Anti-inflammatory and analgesic effects of magnolol. 네이버 미소장
26 Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat. 네이버 미소장
27 Goodman LS, Gilman A. The Pharmacological Basis of Therapeutics. 7th ed. New York: MacMillan. 1985:674. 미소장