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한국학술지인용색인(NRF)
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목적: 근시 정도에 따른 황반 두께를 스펙트럼 영역 빛간섭단층촬영기(SD-OCT)를 이용하여 분석하였다. 대상과 방법: 120명 120안을 구면렌즈대응치에 따라 세 군으로 나누고 SD-OCT로 망막색소상피층(RPE)과 광수용체층(photoreceptorlayer)의 내분절과 외분절의 접합부(IS/OS junction) 사이의 두께를 중심오목과 주변부에서 측정하였다. 또한 평균황반두께, ETDRSsubfield 9개 영역 황반 두께를 비교하였다. 결과: 고도 근시안에서 중심 원의 황반 두께는 정시안과 중등도 근시안보다 매우 두꺼웠으며(p=0.001), 중심오목의 RPE와 IS/OSjunction 사이의 두께 및 바깥쪽 원의 황반두께는 유의하게 얇았다(p=0.001, p=0.002). 구면렌즈대응치와 중심원의 황반 두께는 음의상관관계를 보였으며, 중심오목의 RPE-IS/OS junction 사이의 두께와는 양의 상관관계를 보였다(r=-0.38, p=0.001; r=0.40,p=0.001).결론: 굴절 상태와 황반 두께는 유의한 연관성이 있다. 특히 고도 근시안에서 안구 신장에 따른 효과가 뚜렷하게 나타나며 중심오목에서 광수용체층 외분절의 두께 감소가 나타난다.
Purpose: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). Methods: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. Results: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). Conclusions: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes.
Purpose: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). Methods: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. Results: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). Conclusions: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes.
권호기사
참고문헌 (42건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Prevalence and risk factors for refractive errors in an adult inner city population.  |
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| 2 | Refractive status in the Beaver Dam Eye Study. |
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| 3 | Prevalence and risk factors for refractive errors in adult Chinese in Singapore. |
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| 4 | Prevalence of Myopia in 19-year-old Korean Males: The Relationship between the Prevalence and Education or Urbanization | 소장 |
| 5 | Apple DJ, Fabb MF. Clinicopathologic Correlation of Ocular Disease: a Text and Stereoscopic Atlas. St. Louis: CV Mosby,1978;39-44. | 미소장 |
| 6 | Yanoff M, Fine BS. Ocular Pathology: A Text and Atlas.Philadelphia: Harper & Row, 1982;513-4. | 미소장 |
| 7 | Use of optical coherence tomography to assess variations in macular retinal thickness in myopia. |
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| 8 | [Determination of retinal thickness in relation to the age and axial length using optical coherence tomography]. |
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| 9 | MACULAR THICKNESS MEASUREMENTS IN HEALTHY SUBJECTS WITH DIFFERENT AXIAL LENGTHS USING OPTICAL COHERENCE TOMOGRAPHY |
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| 10 | Quantitative in vivo retinal thickness measurement in chinese healthy subjects with retinal thickness analyzer. |
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| 11 | POSTERIOR POLE RETINAL THICKNESS MEASUREMENTS BY THE RETINAL THICKNESS ANALYZER IN HEALTHY CHINESE SUBJECTS |
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| 12 | Lim MC, Hoh ST, Foster PJ, et al. Use of optical coherence tomography to assess variations in macular retinal thickness in myopia. nvest Ophthalmol Vis Sci 2005;46:974-8. | 미소장 |
| 13 | Regional variations in the relationship between macular thickness measurements and myopia. |
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| 14 | Wu PC, Chen YJ, Chen CH, et al. Assessment of macular retinal thickness and volume in normal eyes and highly myopic eyes with third-generation optical coherence tomography. Eye 2008;22:551-5. | 미소장 |
| 15 | Photoreceptor Inner and Outer Segment Defects in Myopic Foveoschisis |
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| 16 | Refractive Error and Ethnicity in Children |
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| 17 | Epidemiologic study of the prevalence and severity of myopia among schoolchildren in Taiwan in 2000. |
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| 18 | Clinical assessment of mirror artifacts in spectral-domain optical coherence tomography. |
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| 19 | Early Treatment Diabetic Retinopathy Study Design and Baseline Patient Characteristics |
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| 20 | Etiopathogenesis and management of high-degree myopia. Part I. |
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| 21 | The Prevalence of Refractive Errors Among Adults in the United States, Western Europe, and Australia |
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| 22 | Saw SM, Gazzard G, Shih-Yen EC, Chua WH. Myopia and associated pathological complications. Ophthalmic Physiol Opt 2005;m25:381-91 | 미소장 |
| 23 | Retinal and Choroidal Biometry in Highly Myopic Eyes with Spectral-Domain Optical Coherence Tomography |
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| 24 | Ocular risk factors for choroidal neovascularization in pathologic myopia. |
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| 25 | Axial Length Measurements and Fundus Changes of the Myopic Eye |
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| 26 | Pathologic findings in pathologic myopia. |
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| 27 | Lamina cribrosa thickness and spatial relationships between intraocular space and cerebrospinal fluid space in highly myopic eyes. |
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| 28 | McDonnell JM. Ocular embryology and anatomy. In: Ogden TE, ed. Retina. Vol. 1. St Louis: CV Mosby, 1989; 5-16. | 미소장 |
| 29 | Thickness changes in the fovea and peripapillary retinal nerve fiber layer depend on the degree of myopia. | 소장 |
| 30 | Song WK, Lee SC, Lee ES, et al. Macular Thickness Variations with Sex, Age, and Axial Length in Healthy Subjects: a Spectral | 미소장 |
| 31 | Domain-Optical Coherence Tomography Study. Invest Ophthalmol Vis Sci 2010;51:3913-8. | 미소장 |
| 32 | Intersubject variability of foveal cone photoreceptor density in relation to eye length. |
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| 33 | A role for photoreceptor outer segments in the induction of deprivation myopia. |
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| 34 | Rostgaard J, Qvortrup K. A note about retinal structure and visual acuity. A light microscopic study of the cones in fovea centralis. Acta Ophthalmol Scand 1999;77:45-9. | 미소장 |
| 35 | Multifocal electroretinogram in myopia. |
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| 36 | Investigation of changes in the myopic retina using multifocal electroretinograms, optical coherence tomography and peripheral resolution acuity |
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| 37 | Retinal thinning in tree shrews with induced high myopia: optical coherence tomography and histological assessment. |
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| 38 | The spatial organization of tyrosine hydroxylase-immunoreactive amacrine cells in the chicken retina and the consequences of myopia. |
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| 39 | Kanai K, Abe T, Murayama K, Yoneya S. Retinal thickness and changes with age. Nippon Ganka Gakkai Zasshi 2002;106:162-5. | 미소장 |
| 40 | Macular Thickness Changes with Age in Normal Subjects Measured by Optical Coherence Tomography | 소장 |
| 41 | Mean Macular Volume in Normal Korean Eyes Measured by Spectral-domain Optical Coherence Tomography | 소장 |
| 42 | Macular thickness assessment in healthy eyes based on ethnicity using Stratus OCT optical coherence tomography. |
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