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In this study, antioxidant and free radical scavenging activities of the natural antioxidative compound, pyrogallol-phloroglucinol-6,6'-bieckol (PPB) isolated from brown algae, Ecklonia cava was assessed in vitro by measuring the radical scavenging activities (DPPH, alkyl, hydroxyl, and superoxide) using electron spin resonance (ESR) spectrometry, intracellular reactive oxygen species (ROS) scavenging activity, and DNA damage assay. According to the results of these experiments, the scavenging activity PPB against difference radicals was in the following order: DPPH, alkyl, hydroxyl, and superoxide radicals (IC_(50); 0.90, 2.54, 62.93 and 109.05 μM). The antioxidant activities of PPB were higher than that of the commercial antioxidant, ascorbic acid. Furthermore, PPB effectively inhibited DNA damage induced by H_2O_2. These results suggest that the natural antioxidative compound, PPB, can be used by the natural food industry.

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기사명 저자명 페이지 원문 목차
Evaluation of antioxidant properties of a new compound, pyrogallol-phloroglucinol-6,6'-bieckol isolated from brown algae, Ecklonia cava Sung-Myung Kang, Seung-Hong Lee, Soo-Jin Heo, Kil-Nam Kim, You-Jin Jeon pp.495-502

The anti-obesity effect of Lethariella cladonioides in 3T3-L1 cells and obese mice Ju-Hyun Sung, Jeong-Woo Chon, Mi-Ae Lee, Jin-Kyung Park, Jeong-Taek Woo, Yoo Kyoung Park pp.503-510

Hog millet(Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice Mi-Young Park, Hwan-Hee Jang, Jung Bong Kim, Hyun Nye Yoon, Jin-Young Lee, Young-Min Lee, Jae-Hyun Kim, Dong-Sik Park pp.511-519

Folic acid supplementation reduces oxidative stress and hepatic toxicity in rats treated chronically with ethanol Soo-Jung Lee, Myung-Hee Kang, Hyesun Min pp.520-526

Association between ESR1 rs1884051 polymorphism and dietary total energy and plant protein intake on obesity in Korean men Miae Doo, Yangha Kim pp.527-532

Coconut-derived D-xylose affects postprandial glucose and insulin responses in healthy individuals Yun Jung Bae, Youn-Kyung Bak, Bumsik Kim, Min-Sun Kim, Jin-Hee Lee, Mi-Kyung Sung pp.533-539

The effect of carrot juice, β-carotene supplementation on lymphocyte DNA damage, erythrocyte antioxidant enzymes and plasma lipid profiles in Korean smoker Hye-Jin Lee, Yoo Kyoung Park, Myung-Hee Kang pp.540-547

The estimated daily manganese intake of Korean children aged 11-12 Yun Jung Bae, Mi Kyeong Choi pp.548-552

Portion sizes of foods frequently consumed by the Korean elderly : data from KNHANES IV-2 Sook-Bae Kim, Soon-Kyung Kim, Se-Na Kim, So-Young Kim, Young-Sook Cho, Mi-Hyun Kim pp.553-559

Association between adherence to the Korean food guidance system and the risk of metabolic abnormalities in Koreans Hyun Ju Jung, Sung Nim Han, SuJin Song, Hee Young Paik, Hyun Wook Baik, Hyojee Joung pp.560-568

Dietary patterns are associated with physical growth among school girls aged 9-11 years Hwa Young Noh, Yoon Ju Song, Jung Eun Lee, Hyojee Joung, Min Kyung Park, Shan Ji Li, Hee-Young Paik pp.569-577

An exploratory study of compliance with dietary recommendations among college students majoring in health-related disciplines : application of the transtheoretical model Laura H. McArthur, Roman Pawlak pp.578-584

참고문헌 (25건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 3rd ed. New York: Oxford University Press; 1999. p.1-35. 미소장
2 Branen AL. Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene. J Am Oil Chem Soc 1975;52:59-63. 미소장
3 Antioxidant activity and free radical scavenging capacity between Korean medicinal plants and flavonoids by assay-guided comparison 네이버 미소장
4 Antioxidant capacity of medicinal plants from the Province of Cordoba (Argentina) and their in vitro testing in a model food system 네이버 미소장
5 Heo SJ, Kim JP, Jung WK, Lee NH, Kang HS, Jun EM, Park SH, Kang SM, Lee YJ, Park PJ, Jeon YJ. Identification of chemical structure and free radical scavenging activity of diphlorethohydroxycarmalol isolated from a brown alga, Ishige okamurae. J Microbiol Biotechnol 2008;18:676-81. 미소장
6 Antioxidant effects of phlorotannins isolated from Ishige okamurae in free radical mediated oxidative systems. 네이버 미소장
7 Rice-Evans CA, Sampson J, Bramley PM, Holloway DE. Why do we expect carotenoids to be antioxidants in vivo? Free Radic Res 1997;26:381-98. 미소장
8 Guiry MD, Blunden G. Seaweed Resources in Europe: Uses and Potential. New York: John Wiley & Sons Ltd.; 1991. p.335-51. 미소장
9 Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical 네이버 미소장
10 DNA breaking activity of the carbon-centered radical generated from 2,2'-azobis(2-amidinopropane) hydrochloride (AAPH). 네이버 미소장
11 [23] Spin trapping of superoxide and hydroxyl radicals 네이버 미소장
12 ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers 네이버 미소장
13 Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays 네이버 미소장
14 Ahn GN, Kim KN, Cha SH, Song CB, Lee J, Heo MS, Yeo IK, Lee NH, Jee YH, Kim JS, Heu MS, Jeon YJ. Antioxidant activities of phlorotannins purified from Ecklonia cava on free radical scavenging using ESR and H2O2-mediated DNA damage. Eur Food Res Technol 2007;226:71-9. 미소장
15 A New Phlorotannin from the Brown Alga Ecklonia stolonifera 네이버 미소장
16 Anti-HIV-1 activity of phloroglucinol derivative, 6,6′-bieckol, from Ecklonia cava 네이버 미소장
17 Kappus H. Lipid peroxidation: Mechanism and biological relevance. In: Aruoma OI, Halliwell B, editors. Free Radicals and Food Additives. New York: Talyor and Francis; 1991. p.59-75. 미소장
18 Senevirathne M, Kim SH, Jeon YJ. Protective effect of enzymatic hydrolysates from highbush blueberry (Vaccinium corymbosum L.) against hydrogen peroxide-induced oxidative damage in Chinese hamster lung fibroblast cell line. Nutr Res Pract 2010;4:183-90. 미소장
19 Antioxidant activity and total phenolic content of ethanolic extract of Caesalpinia bonducella seeds 네이버 미소장
20 Antioxidant activity of polyphenol and anthocyanin extracts from fruits of Kadsura coccinea (Lem.) A.C. Smith 네이버 미소장
21 Assessment of in vitro antioxidant capacity and polyphenolic composition of selected medicinal herbs from Leguminosae family in Peninsular Malaysia 네이버 미소장
22 The antioxidant capacity and polyphenol content of organic and conventional retail vegetables after domestic cooking 네이버 미소장
23 Antioxidant and antiradical activities of flavonoids. 네이버 미소장
24 Evaluation of the total peroxyl radical-scavenging capacity of flavonoids: structure-activity relationships. 네이버 미소장
25 Antioxidant activities of phlorotannins isolated from Japanese Laminariaceae 네이버 미소장

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