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한국학술지인용색인(NRF)
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초록보기
숙성된 인삼은 인간의 건강을 회복시키고 향상시키는 강장제로서 알려져 있으며, 백삼보다 더 많은 약리적인 활성을 가진다고 알려져 왔다. 전이 가능한 종양, 림프구 증식과 쥐간의 지질과산화에 대한 숙성된 인삼의 효과도 연구 되었다. 본 연구는 3가지 인삼 추출물의 항산화와 항노화 효과를 평가하기 위해서 실험하게 되었다. 시장에서 이미 만들어진 홍삼엑기스를 사용하였고, 그 외 수삼, 건삼을 구매하여 홍삼제조기로 만들어진 추출물로 실험에 사용하였다. 숙성된 인삼의 3가지 추출물들은 superoxide radical 소거 활성, hydroxyl radical 소거 활성, 리놀산 자동산화 억제, 섬유아세포에서 collagenase 억제와 collagen 합성의 효과를 연구했다. 숙성시켜 만든 수삼은 100 ug/mL의 농도에서 가장 높은superoxide radical 소거 활성뿐만 아니라 vitamin C보다 더 높은 hydroxyl radical 소거 활성을 나타냈다. 또한 리놀산 자동산화 억제, collagen 합성과 collagenase 억제에서 가장 높은 활성을 보였다.
Steamed ginseng is well known as a tonic medicine for restoring and enhancing human health. Steamed ginseng had more pharmacologically activity than white ginseng. The effects of steamed ginseng on transplantable tumors, proliferation of lymphocyte and rat liver lipid peroxidation were studied. This study was performed to evaluate the antioxidation and antiwrinkle effects of three ginseng extracts. Raw ginseng (RGS) and dried ginseng (DGS) mature like red ginseng in addition to the ready-made red ginseng (GS) purchased in the market, were steamed and extracted by red ginseng extractor. Three extracts of steamed ginseng were investigated to determine effects of superoxide radical scavenging activity, hydroxyl radical scavenging activity, autooxidation inhibition of linoleic acid, collagenase inhibition and collagen synthesis in normal fibroblast. RGS showed not only the highest superoxide radical scavenging activity at a concentration of 100 ug/mL but also th hydroxyl radical scavenging activity higher than vitamin C. Also RGS showed the highest activity in inhibition of autooxidation of linolic acid, collagen synthesis, and collagenase inhibition.
Steamed ginseng is well known as a tonic medicine for restoring and enhancing human health. Steamed ginseng had more pharmacologically activity than white ginseng. The effects of steamed ginseng on transplantable tumors, proliferation of lymphocyte and rat liver lipid peroxidation were studied. This study was performed to evaluate the antioxidation and antiwrinkle effects of three ginseng extracts. Raw ginseng (RGS) and dried ginseng (DGS) mature like red ginseng in addition to the ready-made red ginseng (GS) purchased in the market, were steamed and extracted by red ginseng extractor. Three extracts of steamed ginseng were investigated to determine effects of superoxide radical scavenging activity, hydroxyl radical scavenging activity, autooxidation inhibition of linoleic acid, collagenase inhibition and collagen synthesis in normal fibroblast. RGS showed not only the highest superoxide radical scavenging activity at a concentration of 100 ug/mL but also th hydroxyl radical scavenging activity higher than vitamin C. Also RGS showed the highest activity in inhibition of autooxidation of linolic acid, collagen synthesis, and collagenase inhibition.
권호기사
참고문헌 (29건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | S. H. Kim, H. Jung, Y. C. Shin, and S. G. Ko, Research of traditional herbal medicines for antiaging, Inhibition effect of wrinkle and whitening effect in the skin, Korean J. Oriental Physiology and Pathology, 22(3), 691 (2008). | 미소장 |
| 2 | Skin aging and photoaging: An overview  |
미소장 |
| 3 | W. S. Yang, Y. M. Kim, E. H. Kim, Y. B. Seu, and Y. J. Yang, Anti-wrinkle effect of cosmetics- containing duchesnea indica extract, J. Soc. Cosmet. Scientists Korea, 36(4), 281 (2010). | 미소장 |
| 4 | K. J. Park, S. H. Park, and J. K. Kim, Anti-wrinkle activity of lindera obtusiloba extract, J. Soc. Cosmet. Scientists Korea, 35(4), 317 (2009). | 미소장 |
| 5 | Mechanisms of Korean red ginseng and herb extracts(KTNG0345) for anti-wrinkle activity | 소장 |
| 6 | Effects of Korean red ginseng and herb extracts mixture (KTNG0345) on procollagen biosynthesis and matrix metalloproteinase-1 activity in human dermal fibroblast | 소장 |
| 7 | Anti-Wrinkle Effects of Korean Rice Wine Cake on Human Fibroblast | 소장 |
| 8 | E. J. Kim, M. K. Kim, X. J. Jin, J. H. Oh, J. E. Kim, and J. H. Chung, Skin aging and photoaging alter fatty acids composition, including 11,14,17-eicosatrienoic acid, in the epidermis of human skin, J. Korean Med. Sci., 25(6), 980 (2010). | 미소장 |
| 9 | Anti-wrinkle Activity of Acanthopanax senticosus Extract in Ultraviolet B (UVB)-induced Photoaging | 소장 |
| 10 | Effect of Korean red ginseng on collagen biosynthesis and MMP-I activity in human dermal fibroblast | 소장 |
| 11 | Promoting Synthesis of Collagen from Angelica dahurica Root | 소장 |
| 12 | Collagen fibrillogenesis in vitro: interaction of types I and V collagen regulates fibril diameter. |
미소장 |
| 13 | G. J. Fisher, S. Datta, H. S. Talwar, Z. Q. Wang, J. Varani, S. Kang, and J. J. Voorhees, Molecular basis of sun-inducedpremature ageing and retinoid antagonism, Nature, 379(25), 335 (1996). | 미소장 |
| 14 | UV-light-induced signal cascades and skin aging. |
미소장 |
| 15 | Effect of Korean Red Ginseng on Blood Pressure and Aortic Vascular(endothelial) Histological Changes in Rats | 소장 |
| 16 | H. Y. Kim, E. K. Mo, and C. K. Sung, The effect of red ginseng extract on fermentation of baechu kimchi, Korean J. Food Preserv, 17(4), 555 (2010). | 미소장 |
| 17 | S. H. Lee, J. I. Kang, and S. Y. Lee, Saponin composition and physico-chemical properties of korean red ginseng extract as affected by ex- tracting conditions. J. Korean Soc. Food Sci. Nutr., 37(2), 256 (2008). | 미소장 |
| 18 | Scavenging Effect of Korean Medicinal Plants on the Peroxynitrite and Total ROS | 소장 |
| 19 | Y. Fugita, I. Urea, Y. Morimoto, M. Nakajima, C. Hatano, and T. Okuda, Studies on inhibition mechanism of autoxidation by tannins and flavonoids, Yakugaku Zasshi, 108(6), 591 (1988). | 미소장 |
| 20 | I. D. Kim, R. H. Kwon, Y. Y. Heo, H. J. Jung, H. Y. Kang, and B. J. Ha, Supercritical extraction of oriental Herb : Anti-aging and anti-wrinkle effects, Korean J. Biotechnol. Bioeng., 23(6), 529 (2008). | 미소장 |
| 21 | Anti-oxidant Activities and Anti-inflammatory Effects on Artemisia scoparia | 소장 |
| 22 | W. K. Cho and J. H. Choi, Effects of pyroligneous liquor on oxygen radical and their scavenger enzymes in liver of CD rats, The Korean Nutrition Society, 40(2), 111 (2007). | 미소장 |
| 23 | The nature of oxidants and antioxidant systems in the inhibition of mutation and cancer |
미소장 |
| 24 | R. Manian, N. Anusuya, P. Siddhuraju, and S. Manian, The antioxidant activity and free radical scavenging potential of two different solvent extracts of Camellia sinensis (L.) O. Kuntz, Ficus bengalensis L. and Ficus racemosa L, Food Chemistry, 107(3), 1000 (2008). | 미소장 |
| 25 | J. A. Lim, B. W. Yun, and S. H. Back, Antioxidative activity and nitrite scavenging ability of methanol extract from Salvia plebeia R. Br., Korean J. Medicinal Crop Sci., 15(3), 183 (2007). | 미소장 |
| 26 | Protective Effects of Aucubin Isolated from Eucommia ulmoides against UVB-Induced Oxidative Stress in Human Skin Fibroblasts(Pharmacognosy) |
미소장 |
| 27 | W. S. Choi, A study on biological activities and anti- oxidative and-inflammatory effects of aloe, master thesis, konkuk university, seoul, Korea (2008). | 미소장 |
| 28 | Free radical scavenging activity of red ginseng aqueous extracts |
미소장 |
| 29 | H. Chun and D. D. Kitts, Free radical scavenging capacity as related to antioxidant activity and ginsenoside composition of asian and north american ginseng extracts, Journal of the American Oil Chemists' Society, 78(3), 249 (2001). | 미소장 |
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