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초록보기

The objective of this work was to investigate the existence of polymorphs and pseudopolymorphs of aceclofenac which is a peripherally acting, non-steroidal anti-inflammatory analgesic with anti-inflammatory, antiarthritic and antipyretic activities. Three crystal forms of aceclofenac have been isolated by recrystallization and characterized by differential scanning calorimetry (DSC),powder X-ray diffractometry (PXRD) and thermogravimetric analysis. The DSC and PXRD patterns of the three crystal forms of aceclofenac were different respectively.

After storage of 1 month at 0 % RH (silica gel, 20 C),52 % RH (saturated solution of Na2Cr2O72H2O/20 C)and 95 % RH (saturated solution of Na2HPO4/20 C),Form 1 and Form 3 (from methylethyl ketone) were not transformed, but Form 2 (from DMSO) was transformed to Form 1 at 95 % RH.

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Thefeasibility study of transdermal drug delivery systems for antidepressants possessing hydrophilicity or hydrophobicity Jong-Suep Baek, Ji-Ho Lim, Jae-Woo So, Jae-Il Kim, Tae-Wan Lee, Sung-Joo Hwang, Sang-Chul Shin, Soo-Jin Kim, Cheong-Weon Cho pp.109-114

Preparation and in vitro evaluation of celecoxib-amino acid conjugates as a colon specific prodrug Yonghyun Lee, Eun Hee Jung, Hyunjung Kim, Jeong-Hyun Yoon, Dae-Duk Kim, Yunjin Jung pp.115-120

Preparation and in vivo evaluation of immediate-release pellet containing celecoxib solid dispersion Chun-Woong Park, Nguyen-Thach Tung, Dao-Danh Son, Ju-Young Kim, Yun-Seok Rhee, Seung-Yeop Kang, Shin-Ae Park, Kyu-Mok Hwang, Tack-Oon Oh, Jung-Myung Ha … [et al.] pp.121-126

Solid state of aceclofenac : characterization, transformation Jung Soon Song, Young Taek Sohn pp.127-131

Pharmacokinetic study of mucoadhesive metformin pellets in rats Jingshu Piao, Ji-Eun Lee, Dae Hwan Shin, Jin-Seok Kim pp.133-137

Development of cataplasmic transdermal drug delivery system containing eutectic mixture of lidocaine and prilocaine Myung-Kwan Chun, Kamal Hossain, Seung-Hyuk Choi, Sang-Jun Ban, Hwansig Moon, Hoo-Kyun Choi pp.139-146

Application of biopharmaceutics classification system(BCS) in drug transport studies across human respiratory epithelial cell monolayers Hyun-Jong Cho, Prabagar Balakrishnan, Hongxia Lin, Min-Koo Choi, Dae-Duk Kim pp.147-153

Recent advances in PLGA particulate systems for drug delivery Jin-Seok Choi, Kyuhwa Seo, Jin-Wook Yoo pp.155-163

참고문헌 (18건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
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10 Matsumoto T, Kaneniwa N, Higuchi S, Otsuka M (1991) Effects oftemperature and pressure during compression on polymorphictransformation and crushing strength of chlopropamide tablets.J Pharm Pharmacol 43:74–78 미소장
11 Opalchenova G, Kalinkova GN (1997) Evaluation of a newpolymorph azlocillin sodium by its antibacterial activity. Int JPharm 153:263–265 미소장
12 Otsuka M, Hasegawa H, Matsuda Y (1999) Effect of polymorphicforms of bulk powders on pharmaceutical properties of carbamazepinegranules. Chem Pharm Bull 47:852–856 미소장
13 Sohn YT (2007) Crystal forms of an angiotensin II receptor antagonistBR-A657. J. Therm. Anal. Cal. 89:799–802 미소장
14 Song HO, Sohn YT (2010) Crystal forms of SK-3530. Arch. Pharm.Res. 12:2033–2036 미소장
15 Ward DE, Veys EM, Bowdler JM, Roma J (1995) Comparison ofaceclofenac with diclofenac in the treatment of osteoarthritis.Clin Rheumatol 14:656–662 미소장
16 Wong MWY, Mitchell AG (1992) Physicochemical characterizationof a phase change produced during the wet granulation ofchlorpromazine hydrochloride and its effects on tableting. Int JPharm 88:261–273 미소장
17 Yamamura S, Momose Y (2001) Quantitative analysis of crystallinepharmaceuticals in powders and tablets by a pattern-fittingprocedure using X-ray powder diffraction data. Int J Pharm212:203–212 미소장
18 Yoshinari T, Forbes RT, York P, Kawashima Y (2002) Moistureinduced polymorphic transition of mannitol and its morphologicaltransformation. Int J Pharm 247:69–77 미소장

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