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The herbs of Orostachys japonicus (Crassulaceae) have been used to treat gastric cancer, gastric ulcer or hemorrhage. Flavonoid glycosides, mainly kaempferol (Kp)- and quercetin (Qc) glycosides, have been isolated from O. japonicus; however, no quantitative information on those flavonol glycosides and no peroxynitrite-scavenging activity of the Orostachys extracts have been reported. In this study, Kp- and Qc glycosides were qualitatively and quantitatively analyzed by high-performance liquid chromatography (HPLC) in eight Orostachys and a Meterostachys species including O. japonicas, O. margaritifolius, O. chongsunensis, O. minuta, O. ramosus, O. malacophylla, O. latiellipticus, O. iwarenge, O. iwarenge for. magnus, and Meterostachys sikokiana distributed or cultivated in Korea. Distinctively, O. margaritifolius contained two flavonol 3,7-di-O-glycosides of Kp 3,7-di-O-glucoside and Kp 3-rhamnosyl-7-glucoside, but O. japonicus had two flavonol 3-O-rutinosides, Kp 3-rutinoside and Qc 3-rutinoside. The three species of O. margaritifolius (24.36 mg/g MeOH extract), O. japonicus (21.28 mg/g), and O. minuta (19.50 mg/g) showed relatively higher flavonoid contents. The flavonol glycosides were analyzed using eight standard compounds (Kp, Qc, Qc 3-O-rhamnoside, Qc 3-O-glucoside, Kp 3-O-rutinoside, Qc 3-O-rutinoside, Kp 3-O-rhamnosyl-7-O-glucoside, Kp 3,7-di-O-glucoside). The present HPLC method was validated to verify the linearity, precision, and accuracy. In addition, the peroxynitrite-scavenging activity was also discussed.

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기사명 저자명 페이지 원문 목차
Study on DPPH free radical scavenging and lipid peroxidation inhibitory activities of Vietnamese medicinal plants Phan Thi Anh Dao, Nguyen Xuan Hai, Nguyen Trung Nhan, Tran Le Quan, Nguyen Thi Thanh Mai pp.1-7

An anacardic acid analog from the jellyfish-derived fungus paecilomyces variotii Juan Liu, Famei Li, Yoon Mi Lee, Jian Lin Li, Jongki Hong, Won Duk Yoon, Eui Kyung Kim, Jee H. Jung pp.8-12

Lupane triterpenoids from Pyrus pyrifolia Ji Hye Yoo, Ki Sook Yang pp.13-15

G0/G1 cell cycle arrest and activation of caspases in honokiol-mediated growth inhibition of human gastric cancer cells You-Jin Kang, Hwa-Jin Chung, Hye-Young Min, Jayoung Song, Hyen Joo Park, Ui Joung Youn, KiHwan Bae, Yeong Shik Kim, Sang Kook Lee pp.16-21

Cycloox[y]genase inhibitory components from Portulaca oleracea Jeong Ah Kim, Seo Young Yang, Sangjin Kang, Young Ho Kim pp.22-25

Actinidia arguta protects cultured cerebral cortical neurons against glutamate-induced neurotoxicity via inhibition of [Ca^2+^]_i_ increase and ROS generation Jae-Hee Cho, Hong Kyu Lee, Yeon Hee Seong pp.26-31

High-performance liquid chromatographic quantification of flavonol glycosides in orostachys species Agung Nugroho, Myung-Hoe Kim, Yu Ran Han, Jae Sue Choi, Hee-Juhn Park pp.32-38

High-performance liquid chromatographic quantification and validation of luteolin glycosides from Sonchus brachyotus and their peroxynitrite-scavenging activity Agung Nugroho, Myung-Hoe Kim, Chan Mi Lee, Jae Sue Choi, Sanghyun Lee, Hee-Juhn Park pp.39-46

Screening of α-glucosidase inhibitory activity of Vietnamese medicinal plants : isolation of active principles from Oroxylum indicum Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Hai Xuan Nguyen, Thuy Nghiem Ngoc Huynh, Byung Sun Min pp.47-51

Protective effects of prunus persica flesh extract(PPFE) on UV-induced oxidative stress and matrix metalloproteinases expression in human skin cells Hyen Joo Park, Kwang-Kyun Park, Jae-Kwan Hwang, Won-Yoon Chung, Gi Dae Kim, Min Ai Lee, Sang Kook Lee pp.52-59

Anti-inflammatory effect of Ixeris dentata on ultraviolet B-induced HaCaT keratinocytes Sung-Bae Kim, Ok-Hwa Kang, Joon-Ho Keum, Su-Hyun Mun, Hyun-Jin An, Hyun Ju Jung, Seung-Heon Hong, DongMyong Jeong, Kee-Tae Kweon, Dong-Yeul Kwon pp.60-66

참고문헌 (19건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Drel, V.R., Patcher, P., Vareniuk, I., Pavlov, I., Lyzogulbov, V.V., Grovez, J.T., and Obrosova, I.G., A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice. Eup. J. Pharmacol. 569, 48-58 (2007). 미소장
2 Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan 네이버 미소장
3 Jung, B.S. and Shin, M.K., Dictionary of the Medicinal Plants. Younglim- Sa, Seoul, pp. 600-601 (1990). 미소장
4 Jung, H.J., Choi, J., Nam, J.H., and Park, H.J., Anti-ulcerogenic effects of the flavonoid-rich fraction from the extract of Orostachys japonicus in mice. J. Med. Food 10, 702-706 (2007). 미소장
5 Je Ma, C., Jung, W.J., Lee, K.Y., Kim, Y.C., and Sung, S. H., Calpain inhibitory isolated from Orostachys japonicas. J. Enzyme Inhib. Med. Chem. 24, 676-679 (2009). 미소장
6 Kim, C.H., Park, J.H., Lim, J.K., Lee, K.J., Chung, G.Y., and Jeong, H.J., The activity of antioxidants and suppression of cancer cell proliferation in extracts of Orostachys japonicus A. Berger. Korean J. Med. Crop. Sci. 11, 31-39 (2003). 미소장
7 A new epicatechin gallate and calpain inhibitory activity from Orostachys japonicus 네이버 미소장
8 Leptin-induced endothelial dysfunction in obesity. 네이버 미소장
9 Peroxynitrite-mediated oxidation of dihydrorhodamine 123. 네이버 미소장
10 Park, H.J., Moon, S.H., Kim, J.O., Lee, S.H., and Choi, J.S., A study on the chemical constituents of Orostachys japonicus A. Berger. Kor. J. Pharmacogn., 22, 78-84 (1991). 미소장
11 Park, H.J., Moon, S.H., Park, K.Y., Choi, J.S., Chung, H.Y., Young, H.S., and Suh, S.S., Antimutagenic effect of Orostachys japonicas. Yakhak Hoeji 35, 253-257 (1991). 미소장
12 Park, H.J., Young, H.S., Park, K.Y., Rhee, S.H., Chung, H.Y., and Choi, J.S., Flavonoids from the whole plants of Orostachys japonicas. Arch. Pharm. Res. 14, 167-171 (1991). 미소장
13 Changes in hepatic drug metabolizing enzymes and lipid peroxidation by methanol extract and major compound of Orostachys japonicus 네이버 미소장
14 Phenolic Compounds from Orostachys japonicus having Anti-HIV-1 Protease Activity 소장
15 Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies. 네이버 미소장
16 Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. 네이버 미소장
17 Sreelatha, S., Jeyachitra, A., and Padma, P.R., Antiproliferation and induction of apoptosis by Moringa oleifera leaf extract on human cancer cells. Food Chem. Toxicol. 49, 1270-1275 (2011). 미소장
18 A Novel Flavonol Lyxoside of Orostachys Japonicus Herb 네이버 미소장
19 Yoon, Y., Kim, K.S., Hong, S.G., Kang, B.J., Lee, M.Y., and Cho, D.W., Protective effect of Orostachys japonicus A. Berger on H2O2-induced apoptosis in GT1-1 mouse hypothalamic neuronal cell line. J. Ethnopharmacol. 69, 73-78 (2000). 미소장

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