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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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Objectives：The aim of this study is to investigate the effectiveness of treatment with osmotic-release oral system methylphenidate (OROS-MPH) on quality of life (QOL) in children with attention-deficit hyperactivity disorder (ADHD). Another aim is to assess the relationship between change in QOL and other factors including children’s symptoms and academic performance or parents’ depression and parenting stress.

Methods：A total of 111 medication-naive children with ADHD in a multicenter, open-label, 12-week trial of OROS-MPH completed an evaluation using diverse rating scales at two time points; at baseline and after 12 weeks of treatment. Scales for investigation of children included the Parent Report Form-Children’s Health and Illness Profile-Children’s Edition (PRF-CHIP-CE) on QOL, the ADHD Rating Scale-IV on symptoms, and the Academic Performance Rating Scale (APRS). The Beck Depression Inventory and Parenting Stress Index were used for assessment of their parents.

Results：Total scores for mean PRF-CHIP-CE increased from 207.9±26.7 at baseline to 226.3±25.9 after 12 weeks of treatment (p＜.001). The change of APRS showed the strongest correlation with the increment of PRF-CHIP-CE scores (Pearson coefficient=0.561, p＜.001), even after controlling for other factors (partial correlation coefficient=0.420, p＜.001).

Conclusion：Treatment with MPH-OROS results in improvement of QOL in children with ADHD in Korea. The advance in academic performance plays a key role in this change of QOL.

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기사명 저자명 페이지 원문 목차
청소년용 정신화 프로그램의 학생정신건강 증진효과 평가 문수진, 오소영, 반건호, 홍민하, 민정원, 김봉석, 황준원, 우이혁, 이원혜 pp.109-116

12주 OROS-Methylphenidate 약물 치료 후 ADHD 아동의 삶의 질 변화 김형인, 김붕년, 조수철, 신민섭, 유희정, 김재원, 김지훈, 신윤미, 정운선, 한덕현, 손정우 pp.103-108

단축형 청소년용 정신화 프로그램의 학생정신건강 증진효과 평가 오소영, 문수진, 이원혜, 홍민하, 민정원, 김봉석, 황준원, 우이혁, 반건호 pp.117-126

임상에서 부모-교사 보고의 일치 : SDQ-Kr과 K-CBCL의 비교 김홍규, 안정숙, 김민혁 pp.127-133

소아기 우울장애의 유병률 및 역학적 특성 : 자가평가 연구 최혜원, 이문수, 임명호, 권호장, 하미나, 유승진, 김은정, 백기청 pp.134-142

소아청소년 집단에서 집단 따돌림의 유병률과 이와 관련된 정신병리 현상 권순재, 박태원, 박선희, 양종철, 정영철, 정상근 pp.143-153

소아청소년 자폐 스펙트럼장애에서 메칠페니데이트 사용의 임상적 특징에 대한 후향적 분석 박진박, 이종일, 진혜경, 민혜지, 황준원, 김예니 pp.154-160

참고문헌 (30건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 The worldwide prevalence of ADHD: a systematic review and metaregression analysis. 네이버 미소장
2 Johnston C, Mash EJ. Families of children with attention-deficit/ hyperactivity disorder: review and recommendations for future research. Clin Child Fam Psychol Rev 2001;4:183-207. 미소장
3 Harpin VA. The effect of ADHD on the life of an individual, their family, and community from preschool to adult life. Arch Dis Child 2005;90 Suppl 1:i2-i7. 미소장
4 Riley AW, Coghill D, Forrest CB, Lorenzo MJ, Ralston SJ, Spiel G; ADORE Study Group. Validity of the health-related quality of life assessment in the ADORE study: Parent Report Form of the CHIP- Child Edition. Eur Child Adolesc Psychiatry 2006;15 Suppl 1: I63-I71. 미소장
5 Worse quality of life for children with newly diagnosed attention-deficit/hyperactivity disorder, compared with asthmatic and healthy children. 네이버 미소장
6 Health-Related Quality of Life of Children and Adolescents With Mental Disorders 네이버 미소장
7 Döpfner M, Steinhausen HC, Coghill D, Dalsgaard S, Poole L, Ralston SJ, et al. Cross-cultural reliability and validity of ADHD assessed by the ADHD Rating Scale in a pan-European study. Eur Child Adolesc Psychiatry 2006;15 Suppl 1:I46-I55. 미소장
8 Practitioner review: Quality of life in child mental health--conceptual challenges and practical choices. 네이버 미소장
9 The quality of life of children with attention deficit/hyperactivity disorder: a systematic review. 네이버 미소장
10 Attention-Deficit-Hyperactivity Disorder: An Update 네이버 미소장
11 ADHD treatment with once-daily OROS methylphenidate: interim 12-month results from a long-term open-label study. 네이버 미소장
12 Treating attention-deficit/hyperactivity disorder beyond symptom control alone in children and adolescents: a review of the potential benefits of long-acting stimulants. 네이버 미소장
13 Mattos P, Louzã MR, Palmini AL, Oliveira IR, Rocha FL. A Multicenter, Open-Label Trial to Evaluate the Quality of Life in Adults With ADHD Treated With Long-Acting Methylphenidate (OROS MPH): Concerta Quality of Life (CONQoL) Study. J Atten Disord In Press 2012. 미소장
14 Riley AW, Spiel G, Coghill D, DÖpfner M, Falissard B, Lorenzo MJ, et al. Factors related to health-related quality of life (HRQoL) among children with ADHD in Europe at entry into treatment. Eur Child Adolesc Psychiatry 2006;15 Suppl 1:I38-I45. 미소장
15 Health-related quality of life in children and adolescents who have a diagnosis of attention-deficit/hyperactivity disorder. 네이버 미소장
16 Atomoxetine Treatment in Children and Adolescents with Attention-Deficit/hyperactivity Disorder and Comorbid Oppositional Defiant Disorder 네이버 미소장
17 Depression-like behavior and mechanical allodynia are reduced by bis selenide treatment in mice with chronic constriction injury: a comparison with fluoxetine, amitriptyline, and bupropion 네이버 미소장
18 American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association;2000. 미소장
19 The reliability and validity of Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version- Korean version (K-SADS-PL-K). 소장
20 The Parent Report Form of the CHIP-Child Edition: Reliability and Validity 네이버 미소장
21 The Reliability and Validity of Korean Parent and Teacher ADHD Rating Scale 소장
22 Validation Study of the Korean Academic Performance Rating Scale (K-APRS) Parent Form 소장
23 Han HM, Yeom TH, Shin YW, Kim GH, Yoon DJ, Chung KJ. A standardization study of Beck Depression Inventory in Korea: For normal group (1). J Korean Neuropsychiatr Assoc 1986;25:487-500. 미소장
24 Chung MJ, Shin SJ. Effects of stress, social support and efficacy on Mothers’ parenting behaviors. Child Stud Diverse Contexts 1998;19: 27-42. 미소장
25 Quality of life measurement in children and adolescents: Issues, instruments, and applications 네이버 미소장
26 Recommendations on health-related quality of life research to support labeling and promotional claims in the United States 네이버 미소장
27 Effect of methylphenidate on the quality of life in children with epilepsy and attention deficit hyperactivity disorder: an open-label study using an osmotic-controlled release oral delivery system 네이버 미소장
28 Evaluation of patients' and parents' quality of life in a randomized placebo-controlled atomoxetine study in attention-deficit/hyperactivity disorder. 네이버 미소장
29 Atomoxetine improves patient and family coping in attention deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled study in Swedish children and adolescents. 네이버 미소장
30 Will working memory training generalize to improve off-task behavior in children with attention-deficit/hyperactivity disorder? 네이버 미소장

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