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한국학술지인용색인(NRF)
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Hypercholesterolemia is the presence of high levels of cholesterol in the blood, and it is regarded as a risk factor for cardiovascular disease due to the effects of cholesterol. The objective of this study was to investigate the effects of unripe Rubus coreanus Miquel (uRC) extract on lipid metabolism in hypercholesterolemic mice fed a high cholesterol diet (HC). uRC 50 (unripe R. coreanus 5% ethanol extract 50 mg/kg/day), uRC 100 (unripe R. coreanus 5% ethanol extract 100 mg/kg/day), uRC 300 (unripe R. coreanus 5% ethanol extract 300 mg/kg/day), and BO (borage seed oil containing minimum of 20% γ-linolenic acid 30 mg/kg/day) were orally administered for 60 days after HC. Oral administration of uRC 50, uRC 100, uRC 300, and BO significantly reduced serum total-cholesterol, triglyceride, LDL-cholesterol, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, atherogenic index, and cardiac risk factor levels. Similarly, uRC treatment elevated serum HDL-cholesterol levels. These results suggest that unripe R. coreanus extract could be established as a functional food for the improvement of lipid metabolism.
권호기사
참고문헌 (25건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Effect of Seeds Extract of Paeonia Lactiflora on Antioxidative System and Lipid Peroxidation of Liver in Rats Fed High-Cholesterol Diet | 소장 |
| 2 | Antioxidative activity of green tea polyphenol in cholesterol-fed rats.  |
미소장 |
| 3 | Lipid management: tools for getting to the goal. |
미소장 |
| 4 | Comparison of the Anti-inflammatory Effects of the Extracts from Rubus coreanus and Rubus occidentalis | 소장 |
| 5 | Lee JW, Do JH. 2000. Determination of total phenolic compounds from the fruit of Rubus coreanum and antioxidative activity. J Korean Soc Food Sci Nutr 29: 943-947. | 미소장 |
| 6 | Kwon KH, Cha WS, Kim DC, Shin HJ. 2006. A research and application of active ingredients in Bokbunja (Rubus coreanus Miquel). Korean J Biotechnol Bioeng 21: 405-409. | 미소장 |
| 7 | Kim TG, Park MS, Han HM, Kang SY, Jung KK, Pheu HM, Kim SH. 1999. Inhibitory effects of Terminalia chebula, Sanguisorba officinalis, Rubus coreanus and Rheum palmatum on hepatitis B virus replication in HepG2 2.2.15cells. Yakhak Hoeji 43: 458-463. | 미소장 |
| 8 | Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase. |
미소장 |
| 9 | Fatigue-Alleviating Effect on Mice of an Ethanolic Extract from Rubus coreanus |
미소장 |
| 10 | Son IS, Kim JH, Sohn HY, Son KH, Kim JS, Kwon CS. 2007. Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats. Biosci Biotechnol Biochem 71: 3063-3071. | 미소장 |
| 11 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. |
미소장 |
| 12 | Effects of Mulberry Leaf Extract Feeding on Lipid Status of Rats Fed High Cholesterol Diets | 소장 |
| 13 | Effects of Green Tea, Buckwheat and Grape Leaves Extracts on Lipid Metabolism, Antioxidative Capacity and Antithrombotic Activity in Rats Fed High Cholesterol Diets | 소장 |
| 14 | Rhee SJ, Park HK. 1984. Change of lipid content and histochemical observation in liver of rats fed high fat diet. Korean J Nutr 17: 113-125. | 미소장 |
| 15 | Influence of tannin-rich carob pod fiber on the cholesterol metabolism in the rat. |
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| 16 | Kim SK, Rhee SJ, Rhee IK, Joo GJ, Ha HP. 1998. Effects of dietary xylooligosaccharide on lipid levels of serum in rats fed high cholesterol diet. J Korean Soc Food Sci Nutr 27: 945-951. | 미소장 |
| 17 | Koh KB, Choi MA. 2001. Effect of Cordyceps militaris on lipid metabolism in rats fed cholesterol diet. Korean J Nutr 34: 265-270. | 미소장 |
| 18 | Influence of background composition of the diet on the lipemic effect of fish oil vs. corn oil in rats. |
미소장 |
| 19 | Effect of cholesterol feeding on DNA damage in male and female Syrian hamsters. |
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| 20 | Steatohepatitis in laboratory opossums exhibiting a high lipemic response to dietary cholesterol and fat. |
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| 21 | Plasma high density lipoproteins. Metabolism and relationship to atherogenesis. |
미소장 |
| 22 | Effects of Extracts of Unripe Black Raspberry and Red Ginseng on Cholesterol Synthesis | 소장 |
| 23 | Effects of Pine Needle on Lipid Composition and TBARS in Rat Fed High Cholesterol | 소장 |
| 24 | Koh JB, Choi MA, Kim JY, Rho MH, Kim DJ. 1999. Effects of tea fungus/kombucha beverage on serum protein levels and enzyme activity in streptozotocin-induced diabetic rats. J Korean Soc Food Sci Nutr 28: 1137-1143. | 미소장 |
| 25 | Lipoprotein analysis. Early methods in the diagnosis of atherosclerosis. |
미소장 |
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