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Monocytes and macrophages regulate host immune system against infectious pathogens. Activated macrophages play an important role in restricting the multiplication and dissemination of pathogens. The concept of alternative activation of macrophages might provide useful insights into pathology of infectious diseases. M1 macrophages (classically activated macrophages) and M2 macrophages (alternatively activated macrophages) are associated with responses to tissue remodeling, pro-inflammatory and anti-inflammatory reactions in various infectious diseases. However, the relevance of macrophage polarization in several infectious diseases was not revealed clearly. Macrophage plasticity and polarization should be considered as a useful conceptual framework for understanding the unknown pathogenesis of infectious diseases. Here we reviewed the recent progress on macrophage polarization and its characters in infectious diseases.

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기사명 저자명 페이지 원문 목차
Toll-like Receptors and NOD-like Receptors in Innate Immune Defense during Pathogenic Infection 조은경, 진효선, 박정규 pp.215-225
Mycobacterium bovis Bacillus Calmette-Guerin(BCG) and BCG-based Vaccines Against Tuberculosis 신성재, 차승빈 pp.236-243
Is Obesity One of Physiological Factors which Exert Influenza Virus-induced Pathology and Vaccine Efficacy? Whajung Cho, Jae-Hwan Nam pp.226-235
The Growth Inhibition Effect on the Causative Bacteria of Bacterial Vaginosis by Bacterial Strains Isolated from the Vagina of a Healthy Woman Nam Woong Yang, Wan-Jin Sihn pp.244-251
Regulation of Host Cell Signaling Pathways by Respiratory Syncytial Virus Nonstructural Protein NS1 and NS2 Han-Bo Shin, Myung-Soo Choi, Chae-Min Yi, Ji-Eun Kim, Su-Ji Jo, Hye-In Kim, Na-Rae Lee, Kyung-Soo Inn pp.283-289
Infection Frequency and Mixed infection on Eight Viruses from Patients with Acute Respiratory Syndromes in Seoul Hee-Jin Ham, Jungim Jang, Sukju Jo, Younghee Oh, Sonil Pak pp.274-282
Comparative Genotype Analysis of Hepatitis A Virus : Two One-Year Studies in South Korea in 2002 and 2011 In Hyuk Baek, Hyun Woong Lee, Hyung Joon Kim, Mi-Ok Song, Seung-Kew Yoon, Jong-Hwa Park, In Sik Chung, Wonyong Kim pp.252-260
Uncleaved Dystrophin Induce Cardiac Myocyte Apoptosis in Coxsackievirus Infected Balb/C Background Mice Heart Byung-Kwan Lim, Jin-Ho Park, Hye-Sun Lee, Yun-Gyeong Lee pp.261-268
Human Adenovirus Type 5 as a Delivery Vector is Not Neutralized in Field Serum Samples of Cattle, Pig, and Goat of Republic of Korea Su-Mi Kim, Hyang-Sim Lee, Kwang-Nyeong Lee, Jong-Hyeon Park, Young-Joon Ko, Byounghan Kim pp.269-273
Macrophage Polarization and Infection 송창화, 임윤지 pp.290-295

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