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Purpose We investigated changing patterns of primary treatment in Korean men with prostate cancer (PC) and impact of sociodemographic factors on treatment choice from a nationwide cohort over 10 years.

Materials and Methods We conducted a cohort study of a 2% nationwide random sample of Korean National Health Insurance. A total of 1,382 patients who had undergone active treatments for newly diagnosed PC between 2003 and 2013 were included. Time trends in primary treatment of PC, including radical surgery, radiation therapy (RT), and androgen deprivation therapy (ADT) were analyzed.

Results Total number of patients undergoing active treatments increased significantly (162%). Surgery cases showed the most significant increase, from 22.4% in 2003 to 45.4% in 2013, while the relative proportion of ADT showed a tendency to decrease from 60.3% in 2003 to 45.4% in 2013, and the relative proportion of RT was variable over 10 years (from 7.2% to 18.4%). While treatment patterns differed significantly according to age (p < 0.001) and income classes (p=0.014), there were differences in primary treatment according to residential area. In multinomial logistic regression analysis, older patients showed significant association with ADT or RT compared to surgery, while patients with higher income showed significant association with surgery.

Conclusion Treatment pattern in Korean PC patients has changed remarkably over the last 10 years.

Sociodemographic factors do affect the primary treatment choice. Our results will be valuable in overviewing changing patterns of primary treatment in Korean PC patients and planning future health policy for PC.

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번호 참고문헌 국회도서관 소장유무
1 Cancer treatment and survivorship statistics, 2014. 네이버 미소장
2 Mortality 네이버 미소장
3 Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2009. 네이버 미소장
4 Prostate cancer risk assessment 네이버 미소장
5 The national cancer data base report on race, age, and region variations in prostate cancer treatment 네이버 미소장
6 Prostate cancer outcomes among older men: insurance status comparisons results from CaPSURE database. 네이버 미소장
7 Determinants of Androgen Deprivation Therapy Use for Prostate Cancer: Role of the Urologist 네이버 미소장
8 Survival of korean adult cancer patients by stage at diagnosis, 2006-2010: national cancer registry study. 소장
9 Screening and prostate-cancer mortality in a randomized European study. 네이버 미소장
10 Mortality results from a randomized prostate-cancer screening trial. 네이버 미소장
11 Practice Patterns of Urologists in Managing Korean Men Aged 40 Years or Younger With High Serum Prostate-specific Antigen Levels 네이버 미소장
12 Rising prostate cancer rates in South Korea 네이버 미소장
13 Time trends and local variation in primary treatment of localized prostate cancer. 네이버 미소장
14 Radical Radiation Therapy for Prostate Cancer in Japan: a Patterns of Care Study Report 네이버 미소장
15 Urologic robotic surgery in Korea : Past and present 소장
16 Comparison of oncological outcomes between retropubic radical prostatectomy and robot-assisted radical prostatectomy: an analysis stratified by surgical experience 네이버 미소장
17 Positive Surgical Margin and Perioperative Complication Rates of Primary Surgical Treatments for Prostate Cancer: A Systematic Review and Meta-Analysis Comparing Retropubic, Laparoscopic, and Robotic Prostatectomy 네이버 미소장
18 Adverse effects of robotic-assisted laparoscopic versus open retropubic radical prostatectomy among a nationwide random sample of medicare-age men. 네이버 미소장
19 THE NEW ECONOMICS OF RADICAL PROSTATECTOMY: COST COMPARISON OF OPEN, LAPAROSCOPIC AND ROBOT ASSISTED TECHNIQUES 네이버 미소장
20 Survival following primary androgen deprivation therapy among men with localized prostate cancer. 네이버 미소장
21 Patient anxiety about prostate cancer independently predicts early initiation of androgen deprivation therapy for biochemical cancer recurrence in older men: a prospective cohort study. 네이버 미소장
22 Characteristics of urologists predict the use of androgen deprivation therapy for prostate cancer. 네이버 미소장
23 EAU Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent—Update 2013 네이버 미소장
24 Geographic and socioeconomic variation in the treatment of prostate cancer. 네이버 미소장
25 Prostate cancer treatment in black and white men: the need to consider both stage at diagnosis and socioeconomic status. 네이버 미소장