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Hyperuricemia, which has been considered as a cause of gout and nephrolithiasis has recently been suggested to be associated with hypertension, coronary heart disease, heart failure, atrial fibrillation, insulin resistance, and nonalcoholic fatty liver disease. Several clinical and experimental studies have supported uric acid (UA) as an independent risk factor for predicting disease development along with the traditional risk factors. The mechanism by which UA causes cardiometabolic disease has not been fully elucidated to date; however, it has been explained by several hypotheses such as oxidative stress, reduced nitric oxide bioavailability, inflammation, endothelial dysfunction, and so on. Although evidence of the preventive and therapeutic effects of UA lowering therapy on cardiometabolic diseases is still insufficient, it is expected to be considered as a new treatment strategy for such diseases through additional, carefully designed, large-scale clinical studies.

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권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Factors associated with dietary adherence to the guidelines for prevention and treatment of hypertension among Korean adults with and without hypertension Jee-Seon Shim, Ji Eun Heo, Hyeon Chang Kim p. 1-11

Potential impact of 2018 Korean Society of Hypertension guidelines on Korean population : a population-based cohort study Ju-Seung Kwun, Sun-Hwa Kim, Si-Hyuck Kang, Chang-Hwan Yoon, Hae-Young Lee, Kwang-Il Kim, Tae-Jin Youn, In-Ho Chae, Cheol-Ho Kim p. 1-8

Blood pressure trajectory modeling in childhood : birth-cohort study Jung Won Lee, Nameun Kim, Bohyun Park, Hyesook Park, Hae Soon Kim p. 1-6

The association of urinary uric acid excretion with ambulatory blood pressure values in patients with chronic kidney disease Ying Xu, Xun Zhou, Yuqi Zheng, Haochen Guan, Chensheng Fu, Jing Xiao, Zhibin Ye p. 1-9

Blood pressure and heart failure Gyu Chul Oh, Hyun-Jai Cho p. 1-8

Hypertension prevalence and its trend in Bangladesh : evidence from a systematic review and meta-analysis Mohammad Ziaul Islam Chowdhury, Meshbahur Rahman, Tanjila Akter, Tania Akhter, Arifa Ahmed, Minhajul Arifin Shovon, Zaki Farhana, Nashit Chowdhury, Tanvir C. Turin p. 1-19

Usefulness of waist-to-height ratio in screening incident hypertension among Japanese community-dwelling middle-aged and elderly individuals Ryuichi Kawamoto, Asuka Kikuchi, Taichi Akase, Daisuke Ninomiya, Teru Kumagi p. 1-9

Uric acid and cardiometabolic diseases Seung Jae Lee, Byeong Kil Oh, Ki-Chul Sung p. 1-7

Renal artery stenosis presenting as preeclampsia Michael Brandon Omar, William Kogler, Satish Maharaj, Win Aung p. 1-5

Highlights of the 2018 Chinese hypertension guidelines Jing Liu p. 1-6

Zonulin as marker of pregnancy induced hypertension : a case control study Ahmed Tijani Bawah, Henry Tornyi, Mohammed Mustapha Seini, Lincoln Toamsoma Ngambire, Francis Agyemang Yeboah p. 1-7

Is the use of RAS inhibitors safe in the current era of COVID-19 pandemic? Sungha Park, Hae Young Lee, Eun Joo Cho, Ki Chul Sung, Juhan Kim, Dae-Hee Kim, Sang-Hyun Ihm, Kwang-il Kim, Il-Suk Sohn, Wook-Jin Chung, Hyeon Chang Kim, Sung Kee Ryu, Wook Bum Pyun, Jinho Shin p. 1-5

Prevalence and determinants of self-reported high blood pressure among women of reproductive age in Benin : a population-based study Michael Ekholuenetale, Amadou Barrow p. 1-9

(The) angiotensin-converting enzyme 2 (ACE2) receptor in the prevention and treatment of COVID-19 are distinctly different paradigms Craig Steven McLachlan p. 1-3

Treatment adherence among patients with hypertension : findings from a cross-sectional study Fahad M. Algabbani, Aljoharah M. Algabbani p. 1-9

Family history of chronic illness, preterm gestational age and smoking exposure before pregnancy increases the probability of preeclampsia in Omo district in southern Ethiopia : a case-control study Kassahun Fikadu, Feleke G/Meskel, Firdawek Getahun, Nega Chufamo, Direslign Misiker p. 1-12

Massive pulmonary thromboembolism combined with transient thyrotoxicosis in an 18 year old girl Tong-Yoon Kim, Sang-Hyun Ihm, Ji Woong Roh, Sungmin Lim, Chan-Seok Park, Hee-Yeol Kim p. 1-6

Association of MYH9-rs3752462 polymorphisms with chronic kidney disease among clinically diagnosed hypertensive patients : a case-control study in a Ghanaian population William K.B.A. Owiredu, Michael Appiah, Christian Obirikorang, Evans Asamoah Adu, Vincent Boima, Ernestine Kubi Amos-Abanyie, Priscilla Abena Akyaw, Eddie-Williams Owiredu, Emmanuel Acheampong p. 1-9

High serum uric acid within the normal range is a useful predictor of hypertension among Japanese community-dwelling elderly women Ryuichi Kawamoto, Daisuke Ninomiya, Taichi Akase, Kikuchi Asuka, Teru Kumagi p. 1-9
Metabolomics profiling in hypertension and blood pressure regulation : a review John O. Onuh, Michel Aliani p. 1-8
Intensive blood pressure lowering : a practical review Miguel Camafort, Josep Redón, Wook Bum Pyun, Antonio Coca p. 1-8
Effect of home blood pressure monitoring for blood pressure control in hypertensive patients taking multiple antihypertensive medications including fimasartan : the FORTE study Jung-Yeon Choi, Kwang-il Kim, Cheol-Ho Kim p. 1-9
Pediatric hypertension : an updated review Mohd Ashraf, Mohd Irshad, Nazir Ahmed Parry p. 1-6
Serum adipocytokines and adiposity as predictive indices of preeclampsia Ahmed Tijani Bawah, Francis Agyemang Yeboah, Salifu Nanga, Huseini Alidu, Robert A. Ngala p. 1-11

참고문헌 (111건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Physiological functions and pathogenic potential of uric acid: A review 네이버 미소장
2 Uric Acid - key ingredient in the recipe for cardiorenal metabolic syndrome. 네이버 미소장
3 Purine-Rich Foods, Dairy and Protein Intake, and the Risk of Gout in Men 네이버 미소장
4 Ethanol-induced hyperuricemia: evidence for increased urate production by activation of adenine nucleotide turnover. 네이버 미소장
5 Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response. 네이버 미소장
6 Johnson RJ, Titte S, Cade JR, Rideout BA, Oliver WJ. Uric acid, evolution and primitive cultures. Semin Nephrol. 2005;25:3–8. 미소장
7 Dalbeth N, Merriman TR, Stamp LK. Gout. Lancet. 2016;388:2039–52. 미소장
8 Recent insights into the pathogenesis of hyperuricaemia and gout 네이버 미소장
9 Regulation of uric acid metabolism and excretion 네이버 미소장
10 Kidney stones 네이버 미소장
11 Hyperuricemia, Gout, and Cardiovascular Disease: An Update 네이버 미소장
12 Gout and hyperuricaemia in the USA: prevalence and trends. 네이버 미소장
13 Prevalence and incidence of gout in Korea: data from the national health claims database 2007–2015 네이버 미소장
14 Liu R, Han C, Wu D, Xia X, Gu J, Guan H, et al. Prevalence of hyperuricemia and gout in Mainland China from 2000 to 2014: a systematic review and meta-analysis. Biomed Res Int. 2015;2015:762820. 미소장
15 Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. 네이버 미소장
16 Prevalence of Gout in the Adult Population of France 네이버 미소장
17 Uric acid-iron ion complexes. A new aspect of the antioxidant functions of uric acid. 네이버 미소장
18 Uric acid and serum antioxidant capacity: a reaction to atherosclerosis? 네이버 미소장
19 Systemic uric acid administration increases serum antioxidant capacity in healthy volunteers. 네이버 미소장
20 Johnson RJ, Sautin YY, Oliver WJ, Roncal C, Mu W, Gabriela Sanchez-Lozada L, et al. Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society? J Comp Physiol B. 2009;179:67–76. 미소장
21 Serum uric acid levels are associated with cardiovascular risk score: A post hoc analysis of the EURIKA study 네이버 미소장
22 Fang J, Alderman MH. Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. JAMA. 2000;283:2404–10. 미소장
23 Yoo TW, Sung KC, Shin HS, Kim BJ, Kim BS, Kang JH, et al. Relationship between serum uric acid concentration and insulin resistance and metabolic syndrome. Circ J. 2005;69:928–33. 미소장
24 Lee JW, Cho YK, Ryan M, Kim H, Lee SW, Chang E, et al. Serum uric acid as a predictor for the development of nonalcoholic fatty liver disease in apparently healthy subjects: a 5-year retrospective cohort study. Gut Liver. 2010;4:378–83. 미소장
25 Relationship of Uric Acid With Progression of Kidney Disease 네이버 미소장
26 Hypertension 네이버 미소장
27 Hyperuricemia and risk of incident hypertension: a systematic review and meta-analysis of observational studies. 네이버 미소장
28 Serum uric acid and arterial hypertension-Data from Sephar III survey. 네이버 미소장
29 Uric acid levels within the normal range predict increased risk of hypertension: a cohort study 네이버 미소장
30 Baseline and Change in Uric Acid Concentration Over Time Are Associated With Incident Hypertension in Large Korean Cohort. 네이버 미소장
31 Lee JJ, Ahn J, Hwang J, Han SW, Lee KN, Kim JB, et al. Relationship between uric acid and blood pressure in different age groups. Clin Hypertens. 2015;21:14. 미소장
32 Longo-Mbenza B, Luila EL, Mbete P, Vita EK. Is hyperuricemia a risk factor of stroke and coronary heart disease among Africans? Int J Cardiol. 1999;71:17–22. 미소장
33 Uric acid and hypertension: a focused review and practical recommendations. 네이버 미소장
34 Hyperuricemia induces endothelial dysfunction 네이버 미소장
35 Uric acid stimulates endothelin-1 gene expression associated with NADPH oxidase in human aortic smooth muscle cells 네이버 미소장
36 Oxidative stress with an activation of the renin–angiotensin system in human vascular endothelial cells as a novel mechanism of uric acid-induced endothelial dysfunction 네이버 미소장
37 Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin–angiotensin system 네이버 미소장
38 Early-onset metabolic syndrome in mice lacking the intestinal uric acid transporter SLC2A9 네이버 미소장
39 Clinical practice. Gout. 네이버 미소장
40 Genotype-based changes in serum uric acid affect blood pressure 네이버 미소장
41 A polymorphism in the major gene regulating serum uric acid associates with clinic SBP and the white-coat effect in a family-based study 네이버 미소장
42 Mortality From Ischemic Heart Disease: Analysis of Data From the World Health Organization and Coronary Artery Disease Risk Factors From NCD Risk Factor Collaboration 네이버 미소장
43 Okura T, Higaki J, Kurata M, Irita J, Miyoshi K, Yamazaki T, et al. Elevated serum uric acid is an independent predictor for cardiovascular events in patients with severe coronary artery stenosis: subanalysis of the Japanese Coronary Artery Disease (JCAD) study. Circ J. 2009;73:885–91. 미소장
44 Hyperuricemia and the risk for subclinical coronary atherosclerosis--data from a prospective observational cohort study. 네이버 미소장
45 Uric Acid Is a Risk Factor for Myocardial Infarction and Stroke 네이버 미소장
46 Hyperuricemia and coronary heart disease mortality: a meta-analysis of prospective cohort studies. 네이버 미소장
47 Significance of serum uric acid levels on the risk of all-cause and cardiovascular mortality. 네이버 미소장
48 Hyperuricemia and coronary heart disease: a systematic review and meta-analysis. 네이버 미소장
49 Serum uric acid is an independent predictor of all‐cause mortality in patients at high risk of cardiovascular disease: A preventive cardiology information system (PreCIS) database cohort study 네이버 미소장
50 Association of uric acid with mortality in patients with stable coronary artery disease 네이버 미소장
51 Elevated serum uric acid and risk of cardiovascular or all-cause mortality in people with suspected or definite coronary artery disease: A meta-analysis 네이버 미소장
52 Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells. 네이버 미소장
53 Uric Acid Stimulates Monocyte Chemoattractant Protein-1 Production in Vascular Smooth Muscle Cells Via Mitogen-Activated Protein Kinase and Cyclooxygenase-2 네이버 미소장
54 The pathogenesis of coronary artery disease and the acute coronary syndromes (1). 네이버 미소장
55 The Role of Urate and Xanthine Oxidase Inhibitors in Cardiovascular Disease 네이버 미소장
56 Impact of allopurinol on risk of myocardial infarction 네이버 미소장
57 Serum Uric Acid and Coronary Heart Disease in 9,458 Incident Cases and 155,084 Controls: Prospective Study and Meta-Analysis 네이버 미소장
58 Association between serum uric acid and cardiovascular mortality and all-cause mortality: a cohort study 네이버 미소장
59 Li X, Meng X, Timofeeva M, Tzoulaki I, Tsilidis KK, Ioannidis JP, et al. Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies. BMJ. 2017;357:j2376. 미소장
60 Keenan T, Zhao W, Rasheed A, Ho WK, Malik R, Felix JF, et al. Causal assessment of serum urate levels in cardiometabolic diseases through a Mendelian randomization study. J Am Coll Cardiol. 2016;67:407–16. 미소장
61 Hyperuricemia predicts adverse outcomes in patients with heart failure 네이버 미소장
62 Gout, allopurinol use, and heart failure outcomes. 네이버 미소장
63 Uric acid in cachectic and noncachectic patients with chronic heart failure: Relationship to leg vascular resistance 네이버 미소장
64 Serum uric acid as an index of impaired oxidative metabolism in chronic heart failure. 네이버 미소장
65 Serum Uric Acid Levels Correlate With Filling Pressures in Systolic Heart Failure 네이버 미소장
66 Elevated serum uric acid levels are associated with diastolic dysfunction in patients with dilated cardiomyopathy 네이버 미소장
67 Uric Acid and Survival in Chronic Heart Failure: Validation and Application in Metabolic, Functional, and Hemodynamic Staging 네이버 미소장
68 Association between hyperuricemia and incident heart failure among older adults: A propensity-matched study 네이버 미소장
69 Uric acid and risk of myocardial infarction, stroke and congestive heart failure in 417,734 men and women in the Apolipoprotein MOrtality RISk study (AMORIS). 네이버 미소장
70 Uric acid level and allopurinol use as risk markers of mortality and morbidity in systolic heart failure 네이버 미소장
71 Uric acid as a predictor of all-cause mortality in heart failure: a meta-analysis. 네이버 미소장
72 Uric acid and risk of heart failure: a systematic review and meta-analysis. 네이버 미소장
73 Hyperuricemia and Incident Heart Failure 네이버 미소장
74 Serum uric acid as a potential marker for heart failure risk in men on antihypertensive treatment: The British Regional Heart Study 네이버 미소장
75 Kanbay M, Segal M, Afsar B, Kang DH, Rodriguez-Iturbe B, Johnson RJ. The role of uric acid in the pathogenesis of human cardiovascular disease. Heart. 2013;99:759–66. 미소장
76 Uric Acid Predicts Clinical Outcomes in Heart Failure: Insights Regarding the Role of Xanthine Oxidase and Uric Acid in Disease Pathophysiology 네이버 미소장
77 Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications 네이버 미소장
78 The increase in serum uric acid concentration caused by diuretics might be beneficial in heart failure. 네이버 미소장
79 Effects of Xanthine Oxidase Inhibition With Allopurinol on Endothelial Function and Peripheral Blood Flow in Hyperuricemic Patients With Chronic Heart Failure 네이버 미소장
80 Xanthine Oxidase Inhibition With Febuxostat Attenuates Systolic Overload-Induced Left Ventricular Hypertrophy and Dysfunction in Mice 네이버 미소장
81 Circulation 네이버 미소장
82 Impact of Oxypurinol in Patients With Symptomatic Heart Failure 네이버 미소장
83 Relation of Elevated Serum Uric Acid Levels to Incidence of Atrial Fibrillation in Patients With Type 2 Diabetes Mellitus 네이버 미소장
84 Association between serum uric acid and atrial fibrillation: a systematic review and meta-analysis. 네이버 미소장
85 Association Between Serum Uric Acid Levels and Atrial Fibrillation Risk 네이버 미소장
86 Association of Serum Uric Acid With Incident Atrial Fibrillation (from the Atherosclerosis Risk in Communities [ARIC] Study) 네이버 미소장
87 Kwon CH, Lee SH, Lee JY, Ryu S, Sung KC. Uric acid and risk of atrial fibrillation in the Korean general population. Circ J. 2018;82:2728–35. 미소장
88 Uric Acid Is Associated With Inflammation, Coronary Microvascular Dysfunction, and Adverse Outcomes in Postmenopausal Women. 네이버 미소장
89 Menopause, postmenopausal hormone use and serum uric acid levels in US women--the Third National Health and Nutrition Examination Survey. 네이버 미소장
90 Hyperuricemia and Atrial Fibrillation:Possible Underlying Mechanisms 네이버 미소장
91 Atrial fibrillation pathophysiology: implications for management. 네이버 미소장
92 Inflammation and the pathogenesis of atrial fibrillation. 네이버 미소장
93 Atrial Fibrillation Increases Production of Superoxide by the Left Atrium and Left Atrial Appendage: Role of the NADPH and Xanthine Oxidases 네이버 미소장
94 Role of Insulin Resistance in Human Disease 네이버 미소장
95 Expert Panel on Detection E, Treatment of High Blood Cholesterol in A. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285:2486–97. 미소장
96 American College of Endocrinology Position Statement on the Insulin Resistance Syndrome 네이버 미소장
97 The metabolic syndrome—a new worldwide definition 네이버 미소장
98 Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. 네이버 미소장
99 Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. 네이버 미소장
100 Raison d'être of insulin resistance: the adjustable threshold hypothesis. 네이버 미소장
101 Facchini F, Chen YD, Hollenbeck CB, Reaven GM. Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration. JAMA. 1991;266:3008–11. 미소장
102 Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia. 네이버 미소장
103 Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis. 네이버 미소장
104 Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome 네이버 미소장
105 Nonalcoholic fatty liver disease. 네이버 미소장
106 Jensen T, Niwa K, Hisatome I, Kanbay M, Andres-Hernando A, Roncal-Jimenez CA, et al. Increased serum uric acid over five years is a risk factor for developing fatty liver. Sci Rep. 2018;8:11735. 미소장
107 High serum uric acid and risk of nonalcoholic fatty liver disease: A systematic review and meta-analysis 네이버 미소장
108 Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism 네이버 미소장
109 Xanthine oxidase in nonalcoholic fatty liver disease and hyperuricemia: One stone hits two birds 네이버 미소장
110 Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes 네이버 미소장
111 High uric acid directly inhibits insulin signalling and induces insulin resistance 네이버 미소장

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